Respiratory supercomplexes: Plasticity and implications

Christina A. Porras; Yidong Bai

doi:10.2741/4327

Respiratory supercomplexes: Plasticity and implications

Christina A. Porras, Yidong Bai

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging.

Original language	English (US)
Pages (from-to)	621-634
Number of pages	14
Journal	Frontiers in Bioscience - Landmark
Volume	20
Issue number	4
DOIs	https://doi.org/10.2741/4327
State	Published - Jan 15 2015

Keywords

Mitochondria
ROS
Respiration
Review
Supercomplex

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

Access to Document

10.2741/4327

Cite this

@article{f60f1956ec124718b5d722e486ec62f5,

title = "Respiratory supercomplexes: Plasticity and implications",

abstract = "The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging.",

keywords = "Mitochondria, ROS, Respiration, Review, Supercomplex",

author = "Porras, {Christina A.} and Yidong Bai",

year = "2015",

month = jan,

day = "15",

doi = "10.2741/4327",

language = "English (US)",

volume = "20",

pages = "621--634",

journal = "Frontiers in Bioscience - Landmark",

issn = "2768-6701",

publisher = "IMR Press Limited",

number = "4",

}

TY - JOUR

T1 - Respiratory supercomplexes

T2 - Plasticity and implications

AU - Porras, Christina A.

AU - Bai, Yidong

PY - 2015/1/15

Y1 - 2015/1/15

N2 - The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging.

AB - The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging.

KW - Mitochondria

KW - ROS

KW - Respiration

KW - Review

KW - Supercomplex

UR - http://www.scopus.com/inward/record.url?scp=84918819897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918819897&partnerID=8YFLogxK

U2 - 10.2741/4327

DO - 10.2741/4327

M3 - Review article

C2 - 25553469

AN - SCOPUS:84918819897

SN - 2768-6701

VL - 20

SP - 621

EP - 634

JO - Frontiers in Bioscience - Landmark

JF - Frontiers in Bioscience - Landmark

IS - 4

ER -

Respiratory supercomplexes: Plasticity and implications

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this