Reproducibility of disc susceptibility tests with haemophilus influenzae

A. L. Barry; J. H. Jorgensen; D. J. Hardy

doi:10.1093/jac/27.3.295

Reproducibility of disc susceptibility tests with haemophilus influenzae

A. L. Barry, J. H. Jorgensen, D. J. Hardy

Pathology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Triplicate susceptibility tests were performed in each of three laboratories with 45 strains of Haemophilus influenzae and a single lot of Haemophilus test medium (HTM) agar plates. Using clarithromycin, erythromycin and chloramphenicol discs, zone sizes varied over ranges averaging only 4.3-5.8 mm. Ampicillin zone sizes were more variable, especially when β-lactamase-producing strains were being tested, but the latter strains were consistently categorized as being resistant. A 94% interpretive consistency was observed with the two macrolides.

Original language	English (US)
Pages (from-to)	295-301
Number of pages	7
Journal	Journal of Antimicrobial Chemotherapy
Volume	27
Issue number	3
DOIs	https://doi.org/10.1093/jac/27.3.295
State	Published - Mar 1 1991

ASJC Scopus subject areas

Pharmacology
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

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