Replicate single-use comparative study of plaque removal with two contemporary manual toothbrushes

Géza T. Terézhalmy, Pat Walters, Robert D. Bartizek, Julie M. Grender, Aaron R. Blesbrock

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose: To compare the plaque removing efficacy of Oral-B Advantage 123 and Colgate 360° manual toothbrushes on a single brushing after a 24-hour void in oral hygiene. Methods: This study had a two-treatment (Advantage 123 versus Colgate 360°), examiner-blind, randomized, four-period (visit) crossover design. At the first (baseline) visit, subjects received a plaque examination using the Rustogi Modified Navy Plaque Index (RMNPI) after which they were instructed to brush for 1 minute in their normal manner with their assigned toothbrush and a marketed dentifrice and unaided by access to a mirror. Post-brushing plaque was then assessed. At three further visits, each separated by a period of 3-8 days, brushes were assigned to subjects according to their treatment sequence and the same brushing and plaque grading procedure as at baseline was followed. Results: 50 subjects were enrolled in the replicate single-use study; all were included in the analysis. Oral-B Advantage 123 was significantly better than Colgate 360° at reducing whole mouth (P= 0.006), gingival margin (P= 0.010) and approximal (P= 0.040) plaque scores.

Original languageEnglish (US)
Pages (from-to)189-192
Number of pages4
JournalAmerican journal of dentistry
Issue number3
StatePublished - Jun 2009

ASJC Scopus subject areas

  • Dentistry(all)


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