Renal cortical necrosis following a colonoscopy

Muhammad Hammadah; Lillian Gaber; Rajeev Raghavan

doi:10.5414/CN107171

Renal cortical necrosis following a colonoscopy

Muhammad Hammadah, Lillian Gaber, Rajeev Raghavan

Research output: Contribution to journal › Article › peer-review

Abstract

A 76-year old African-American male presented with profound renal failure within 2 weeks after a screening colonoscopy. Polyethylene glycol (PEG) was the sole oral preparatory agent. The significantly elevated lactate dehydrogenase (LDH) and biopsy findings were consistent with acute renal cortical necrosis (RCN). PEG is associated with AKI, but the exact mechanism is uncertain. PEG can be biodegraded to diethylene glycol (DEG), which is a nephrotoxic agent associated with RCN. Three months after presentation, the patient remains hemodialysis dependent

Original language	English (US)
Pages (from-to)	67-71
Number of pages	5
Journal	Clinical Nephrology
Volume	79
Issue number	1
DOIs	https://doi.org/10.5414/CN107171
State	Published - 2013
Externally published	Yes

Keywords

Acute kidney injury
Diethylene glycol
Hemodialysis
Polyethylene glycol
Renal cortical necrosis

ASJC Scopus subject areas

Nephrology

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10.5414/CN107171

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Renal cortical necrosis following a colonoscopy

Abstract

Keywords

ASJC Scopus subject areas

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