TY - JOUR
T1 - Religion, spirituality, and depressive symptoms in patients with HIV/AIDS
AU - Yi, Michael S.
AU - Mrus, Joseph M.
AU - Wade, Terrance J.
AU - Ho, Mona L.
AU - Hornung, Richard W.
AU - Cotton, Sian
AU - Peterman, Amy H.
AU - Puchalski, Christina M.
AU - Tsevat, Joel
N1 - Funding Information:
This study was funded by Veterans Affairs Health Services Research and Development grant #ECl 01-195 (PI: Tsevat) and by National Center for Complementary and Alternative Medicine grant R01 AT01147 (PI: Tsevat). Dr. Yi is supported by a National Institute of Child Health and Human Development Career Development Award (K23HD046690). Dr. Tsevat is supported by a National Center for Complementary and Alternative Medicine award (K24 AT001676). Dr. Mrus was a recipient of a Career Development Award (RCD 01011-2) from the Veterans Affairs Health Services Research and Development Service. Dr. Wade is the Canadian Research Chair in Youth and Wellness. Dr. Mrus was employed at GlaxoSmithkline at the time this manuscript was submitted. Dr. Peterman is currently in the Department of Psychology, University of North Carolina at Charlotte,
PY - 2006/12
Y1 - 2006/12
N2 - BACKGROUND: Depression has been linked to immune function and mortality in patients with chronic illnesses. Factors such as poorer spiritual well-being has been linked to increased risk for depression and other mood disorders in patients with HIV. OBJECTIVE: We sought to determine how specific dimensions of religion, spirituality, and other factors relate to depressive symptoms in a contemporary, multi-center cohort of patients with HIV/AIDS. DESIGN: Patients were recruited from 4 medical centers in 3 cities in 2002 to 2003, and trained interviewers administered the questionnaires. The level of depressive symptoms was measured with the 10-item Center for Epidemiologic Studies Depression (CESD-10) Scale. Independent variables included socio-demographics, clinical information, 8 dimensions of health status and concerns, symptoms, social support, risk attitudes, self-esteem, spirituality, religious affiliation, religiosity, and religious coping. We examined the bivariate and multivariable associations of religiosity, spirituality, and depressive symptoms. MEASUREMENTS AND MAIN RESULTS: We collected data from 450 subjects. Their mean (SD) age was 43.8 (8.4) years; 387 (86.0%) were male; 204 (45.3%) were white; and their mean CD4 count was 420.5 (301.0). Two hundred forty-one (53.6%) fit the criteria for significant depressive symptoms (CESD-10 score ≥10). In multivariable analyses, having greater health worries, less comfort with how one contracted HIV, more HIV-related symptoms, less social support, and lower spiritual well-being was associated with significant depressive symptoms (P<.05). CONCLUSION: A majority of patients with HIV reported having significant depressive symptoms. Poorer health status and perceptions, less social support, and lower spiritual well-being were related to significant depressive symptoms, while personal religiosity and having a religious affiliation was not associated when controlling for other factors. Helping to address the spiritual needs of patients in the medical or community setting may be one way to decrease depressive symptoms in patients with HIV/AIDS.
AB - BACKGROUND: Depression has been linked to immune function and mortality in patients with chronic illnesses. Factors such as poorer spiritual well-being has been linked to increased risk for depression and other mood disorders in patients with HIV. OBJECTIVE: We sought to determine how specific dimensions of religion, spirituality, and other factors relate to depressive symptoms in a contemporary, multi-center cohort of patients with HIV/AIDS. DESIGN: Patients were recruited from 4 medical centers in 3 cities in 2002 to 2003, and trained interviewers administered the questionnaires. The level of depressive symptoms was measured with the 10-item Center for Epidemiologic Studies Depression (CESD-10) Scale. Independent variables included socio-demographics, clinical information, 8 dimensions of health status and concerns, symptoms, social support, risk attitudes, self-esteem, spirituality, religious affiliation, religiosity, and religious coping. We examined the bivariate and multivariable associations of religiosity, spirituality, and depressive symptoms. MEASUREMENTS AND MAIN RESULTS: We collected data from 450 subjects. Their mean (SD) age was 43.8 (8.4) years; 387 (86.0%) were male; 204 (45.3%) were white; and their mean CD4 count was 420.5 (301.0). Two hundred forty-one (53.6%) fit the criteria for significant depressive symptoms (CESD-10 score ≥10). In multivariable analyses, having greater health worries, less comfort with how one contracted HIV, more HIV-related symptoms, less social support, and lower spiritual well-being was associated with significant depressive symptoms (P<.05). CONCLUSION: A majority of patients with HIV reported having significant depressive symptoms. Poorer health status and perceptions, less social support, and lower spiritual well-being were related to significant depressive symptoms, while personal religiosity and having a religious affiliation was not associated when controlling for other factors. Helping to address the spiritual needs of patients in the medical or community setting may be one way to decrease depressive symptoms in patients with HIV/AIDS.
KW - AIDS
KW - Depression
KW - HIV
KW - Health status
KW - Mental health
KW - Outcome assessment (health care)
KW - Quality of life
KW - Spirituality
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U2 - 10.1111/j.1525-1497.2006.00643.x
DO - 10.1111/j.1525-1497.2006.00643.x
M3 - Article
C2 - 17083496
AN - SCOPUS:33750493322
VL - 21
SP - S21-S27
JO - Journal of General Internal Medicine
JF - Journal of General Internal Medicine
SN - 0884-8734
IS - SUPPL. 5
ER -