TY - JOUR
T1 - Relative vs. absolute values
T2 - Using patient and population norms for echocardiography in pediatric cardiac transplant recipients
AU - Raczek, Katherine K.
AU - Dorey, Frederick
AU - Wong, Pierre C.
AU - Szmuszkovicz, Jacqueline R.
AU - Menteer, Jondavid
PY - 2010/3
Y1 - 2010/3
N2 - Intrapatient consistency and relative utility of TDI as well as other echocardiographic parameters are incompletely understood in pediatric HTx recipients. We sought to evaluate the relative strength of common echocardiographic parameters used in the evaluation of pediatric HTx recipients, including TDI. We reviewed 388 echocardiograms and 73 catheterizations from 34 pediatric HTx recipients without coronary disease over an 18-month period. Data included systolic and diastolic parameters, with VCFc and mitral annular TDI velocities. We used descriptive statistics, and analyzed intrapatient variability using MSR from one-way anova. Echocardiographic data were compared with invasively measured hemodynamic data. For most echocardiographic parameters, including TDI velocities, intrapatient variability was smaller than total population variability. VCFc was higher than normal in most patients. TDI parameters were approximately 10% slower than in previously published studies of normal subjects. Pediatric HTx normal ranges are not the same as healthy population norms, and the range of findings in healthy HTx recipients without rejection is relatively broad. Serial assessment is important when interpreting echocardiograms in pediatric HTx recipients.
AB - Intrapatient consistency and relative utility of TDI as well as other echocardiographic parameters are incompletely understood in pediatric HTx recipients. We sought to evaluate the relative strength of common echocardiographic parameters used in the evaluation of pediatric HTx recipients, including TDI. We reviewed 388 echocardiograms and 73 catheterizations from 34 pediatric HTx recipients without coronary disease over an 18-month period. Data included systolic and diastolic parameters, with VCFc and mitral annular TDI velocities. We used descriptive statistics, and analyzed intrapatient variability using MSR from one-way anova. Echocardiographic data were compared with invasively measured hemodynamic data. For most echocardiographic parameters, including TDI velocities, intrapatient variability was smaller than total population variability. VCFc was higher than normal in most patients. TDI parameters were approximately 10% slower than in previously published studies of normal subjects. Pediatric HTx normal ranges are not the same as healthy population norms, and the range of findings in healthy HTx recipients without rejection is relatively broad. Serial assessment is important when interpreting echocardiograms in pediatric HTx recipients.
KW - Cardiac transplant
KW - Echocardiography
KW - Pediatrics
KW - Tissue Doppler imaging
UR - http://www.scopus.com/inward/record.url?scp=76449097507&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76449097507&partnerID=8YFLogxK
U2 - 10.1111/j.1399-3046.2009.01176.x
DO - 10.1111/j.1399-3046.2009.01176.x
M3 - Article
C2 - 19413718
AN - SCOPUS:76449097507
SN - 1397-3142
VL - 14
SP - 182
EP - 187
JO - Pediatric Transplantation
JF - Pediatric Transplantation
IS - 2
ER -