Relationships between human blood groups, bacterial pathogens, and urinary tract infections

J. J. Ratner, V. L. Thomas, M. Forland

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Blood groups of 137 patients with acute pyelonephritis and chronic upper tract infection, cystitis, and asymptomatic bacteriuria were compared with those of a normal uninfected control population. In addition, the identified uropathogens were categorized according to the patient's blood group. There was a significant association between the diagnosis of chronic upper tract infection and blood group B as compared with controls (p = <0.05, χ2). Analysis of the bacterial isolates showed that more patients with blood group B had infections with Pseudomonas sp., Klebsiella pneumoniae, and Proteus sp. than was expected; and fewer patients with blood group A had infections with Pseudomonas than predicted (p = <0.05, χ2). There was an increased number of patients in blood group AB with infections caused by Escherichia coli and Klebsiella pneumoniae. These results suggest that an individual's blood group may be a significant factor in the host-response to bacterial invasion and influence the development of infection with certain gram-negative bacilli.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalAmerican Journal of the Medical Sciences
Volume292
Issue number2
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Medicine(all)

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