Relationship between cortisol and cholesterol in men with coronary artery disease and Type A behavior

H. A. Schwertner, R. G. Troxler, G. S. Uhl, W. G. Jackson

    Research output: Contribution to journalArticle

    24 Scopus citations

    Abstract

    To further understand the hormonal mechanisms linking behavior pattern and coronary artery disease (CAD), we investigated the relationship between 0930-hour plasma cortisol and cholesterol in relatively young males who had undergone coronary angiography and in a subgroup of individuals who had undergone the structured interview for classification of behavior pattern. A statistically significant association (p < 0.05) was found between cortisol and cholesterol for individuals who had either minimal CAD (20% to 49% narrowing) or significant CAD (≥50% narrowing), but not for subjects without CAD. An association between cortisol and cholesterol was also found to be significant for the subgroup of individuals with Type A-1 behavior pattern, but not for those with Type A-2, X, or B behavior patterns. The findings suggest that hormonal mechanisms involving cortisol and cholesterol metabolism may be operative in individuals with CAD as well as in individuals with Type A-1 behavior.

    Original languageEnglish (US)
    Pages (from-to)59-64
    Number of pages6
    JournalArteriosclerosis
    Volume4
    Issue number1
    DOIs
    StatePublished - 1984

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

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