Relationship between bone mechanical properties and collagen denaturation

X. Wang; R. A. Bank; J. M. Tekoppele; K. A. Athanasiou; C. M. Agrawal

Relationship between bone mechanical properties and collagen denaturation

X. Wang, R. A. Bank, J. M. Tekoppele, K. A. Athanasiou, C. M. Agrawal

Department of Orthopaedics

Research output: Contribution to conference › Paper › peer-review

3 Scopus citations

Abstract

The percentage of denatured type 1 collagen in baboon bone using a new biochemical method was studied and correlated with the biochemical and physical properties of bone. The results indicate that changes in the failure energy and fracture toughness of bone most likely stem from age-dependent changes in mineral and collagen phases of bone. Structural changes in collagen molecules are significantly correlated with the elastic modulus and failure energy or toughness of bone. Meanwhile, bone mineral content has a significant correlation with the elastic modulus, yield strength and ultimate strength of bone.

Original language	English (US)
Number of pages	1
State	Published - 1998
Event	Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998

Other

Other	Proceedings of the 1998 17th Southern Biomedical Engineering Conference
City	San Antonio, TX, USA
Period	2/6/98 → 2/8/98

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Relationship between bone mechanical properties and collagen denaturation",

abstract = "The percentage of denatured type 1 collagen in baboon bone using a new biochemical method was studied and correlated with the biochemical and physical properties of bone. The results indicate that changes in the failure energy and fracture toughness of bone most likely stem from age-dependent changes in mineral and collagen phases of bone. Structural changes in collagen molecules are significantly correlated with the elastic modulus and failure energy or toughness of bone. Meanwhile, bone mineral content has a significant correlation with the elastic modulus, yield strength and ultimate strength of bone.",

author = "X. Wang and Bank, {R. A.} and Tekoppele, {J. M.} and Athanasiou, {K. A.} and Agrawal, {C. M.}",

year = "1998",

language = "English (US)",

note = "Proceedings of the 1998 17th Southern Biomedical Engineering Conference ; Conference date: 06-02-1998 Through 08-02-1998",

}

TY - CONF

T1 - Relationship between bone mechanical properties and collagen denaturation

AU - Wang, X.

AU - Bank, R. A.

AU - Tekoppele, J. M.

AU - Athanasiou, K. A.

AU - Agrawal, C. M.

PY - 1998

Y1 - 1998

N2 - The percentage of denatured type 1 collagen in baboon bone using a new biochemical method was studied and correlated with the biochemical and physical properties of bone. The results indicate that changes in the failure energy and fracture toughness of bone most likely stem from age-dependent changes in mineral and collagen phases of bone. Structural changes in collagen molecules are significantly correlated with the elastic modulus and failure energy or toughness of bone. Meanwhile, bone mineral content has a significant correlation with the elastic modulus, yield strength and ultimate strength of bone.

AB - The percentage of denatured type 1 collagen in baboon bone using a new biochemical method was studied and correlated with the biochemical and physical properties of bone. The results indicate that changes in the failure energy and fracture toughness of bone most likely stem from age-dependent changes in mineral and collagen phases of bone. Structural changes in collagen molecules are significantly correlated with the elastic modulus and failure energy or toughness of bone. Meanwhile, bone mineral content has a significant correlation with the elastic modulus, yield strength and ultimate strength of bone.

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UR - http://www.scopus.com/inward/citedby.url?scp=0031650391&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:0031650391

T2 - Proceedings of the 1998 17th Southern Biomedical Engineering Conference

Y2 - 6 February 1998 through 8 February 1998

ER -

Relationship between bone mechanical properties and collagen denaturation

Abstract

Other

ASJC Scopus subject areas

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