Relation of echocardiographic wall motion score index and response to dobutamine stress to defibrillation threshold at the time of implantation of a cardiac defibrillator

Ali M. Kizilbash, Paul A. Grayburn, Prasad Anand, Robert C. Kowal, Richard L. Page, Kim Smith, Mohamed H. Hamdan

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Predictors of defibrillation threshold (DFT) at implantation remain poorly defined. It was hypothesized that a greater wall motion score index (WMSI) at rest on echocardiography and an ischemic or biphasic response on dobutamine stress echocardiography (DSE) would predict a greater DFT. Consecutive patients who underwent implantable cardiac-defibrillator implantation underwent echocardiography and DSE. DFT at implantation was assessed using the step-down method. Thirteen men aged 68 ± 10 years with left ventricular ejection fractions of 28 ± 10% participated in the study. DFTs ranged from 5 to 25 J (mean 14 ± 8). A WMSI at rest of <2.5 had a 71% positive predictive value and an 83% negative predictive value for a DFT <15 J. An ischemic or biphasic response during DSE did not predict a greater DFT at implantation.

Original languageEnglish (US)
Pages (from-to)1099-1101
Number of pages3
JournalAmerican Journal of Cardiology
Volume95
Issue number9
DOIs
StatePublished - May 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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