Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer

Medicine and Dentistry

• Coagulation Factor IX 100%
• Toll Like Receptor 9 83%
• Antibody 66%
• Muscle 50%
• Depletion 33%
• Gene Transfer 33%
• Transgene 33%
• Agonist 33%
• Regulatory T Cell 33%
• Obstetric Delivery 16%
• Protein 16%
• Combination Therapy 16%
• Skeletal Muscle 16%
• Antibody Response 16%
• C57BL/6 16%
• Monocyte 16%
• Intramuscular Injection 16%
• Lipopolysaccharide 16%
• Humoral Immunity 16%
• Cellular Infiltration 16%
• Cellular Immunity 16%
• Dendritic Cell 16%
• Viral Gene Delivery System 16%
• T Follicular Helper Cell 16%
• Cytotoxic T-Cell 16%

Biochemistry, Genetics and Molecular Biology

• TLR9 83%
• Antibody 66%
• Agonist 33%
• Transgene 33%
• Transfer Gene 33%
• Regulatory T Cell 33%
• Skeletal Muscle 16%
• Lipopolysaccharide 16%
• Cellular Immunity 16%
• CD8 16%
• Therapeutic Protein 16%
• C57BL 6 Mouse 16%
• Monocyte 16%
• Dendritic Cell 16%
• Humoral Immunity 16%
• Viral Gene Delivery System 16%
• Antibody Response 16%
• Cell Infiltration 16%
• Dose 16%