Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models

Fuyang Li, Kathryn M. Bondra, Samson Ghilu, Adam Studebaker, Qianqian Liu, Joel E. Michalek, Mari Kogiso, Xiao Nan Li, John A. Kalapurakal, C. David James, Sandeep Burma, Raushan T. Kurmasheva, Peter J. Houghton

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Medicine and Dentistry