Regional and physician specialty-associated variations in the medical management of atherosclerotic renal-artery stenosis

David A. Folt, Kaleigh L. Evans, Sravya Brahmandam, Wencan He, Pamela S. Brewster, Shipeng Yu, Timothy P. Murphy, Donald E. Cutlip, Lance D. Dworkin, Kenneth Jamerson, William Henrich, Philip A. Kalra, Sheldon Tobe, Ken Thomson, Andrew Holden, Brian L. Rayner, Liliana Grinfeld, Steven T. Haller, Christopher J. Cooper

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

For people enrolled in Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL), we sought to examine whether variation exists in the baseline medical therapy of different geographic regions and if any variations in prescribing patterns were associated with physician specialty. Patients were grouped by location within the United States (US) and outside the US (OUS), which includes Canada, South America, Europe, South Africa, New Zealand, and Australia. When comparing US to OUS, participants in the US took fewer anti-hypertensive medications (1.9 ± 1.5 vs. 2.4 ± 1.4; P < .001) and were less likely to be treated with an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker (46% vs. 62%; P<.001), calcium channel antagonist (37% vs. 58%; P < .001), and statin (64% vs. 75%; P < .05). In CORAL, the identification of variations in baseline medical therapy suggests that substantial opportunities exist to improve the medical management of patients with atherosclerotic renal-artery stenosis. JAm Soc Hypertens 2015;9(6):443-452.

Original languageEnglish (US)
Pages (from-to)443-452
Number of pages10
JournalJournal of the American Society of Hypertension
Volume9
Issue number6
DOIs
StatePublished - 2015

Keywords

  • Antihypertensive medical therapy
  • Geography
  • Renovascular hypertension

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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