Regeneration of Periodontal Tissues: Guided Tissue Regeneration

Cristina C. Villar, David L. Cochran

Research output: Contribution to journalReview articlepeer-review

123 Scopus citations


The concept that only fibroblasts from the periodontal ligament or undifferentiated mesenchymal cells have the potential to re-create the original periodontal attachment has been long recognized. Based on this concept, guided tissue regeneration has been applied with variable success to regenerate periodontal defects. Quantitative analysis of clinical outcomes after guided tissue regeneration suggests that this therapy is a successful and predictable procedure to treat narrow intrabony defects and class II mandibular furcations, but offers limited benefits in the treatment of other types of periodontal defects.

Original languageEnglish (US)
Pages (from-to)73-92
Number of pages20
JournalDental clinics of North America
Issue number1
StatePublished - Jan 2010


  • Furcation defects
  • Guided tissue regeneration
  • Intrabony defects
  • Membranes
  • Periodontal regeneration

ASJC Scopus subject areas

  • Dentistry(all)


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