Refractoriness to the antigonadotrophic effects of melatonin in male hamsters and its interruption by exposure of the animals to long daily photoperiods

Russel J Reiter, Larry J. Petterborg, Ronald C. Philo

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Exposure of adult male Syrian hamsters to artificially shortened photoperiods in the laboratory was followed by gonadal involution. Return of these animals to long days (light:ddark cycles of 14:10) resulted in regrowth of the reproductive organs, following which the animals were refractory to the normally antigonadotrophic effects of daily melatonin injections given late in the afternoon. When hamsters were kept under naturally shortening photoperiods beginning on October 19, their reproductive organs involuted and remained infantile until the following spring when they again recrudesced to adult size. These animals too were refractory to the inhibitory effects of daily afternoon melatonin injections. The refractory period to melatonin was interrupted by exposure of the animals to long days for 22 weeks.

Original languageEnglish (US)
Pages (from-to)1571-1576
Number of pages6
JournalLife Sciences
Volume25
Issue number18
DOIs
StatePublished - Oct 29 1979

Fingerprint

Photoperiod
Melatonin
Cricetinae
Animals
Refractory materials
Injections
Mesocricetus

ASJC Scopus subject areas

  • Pharmacology

Cite this

Refractoriness to the antigonadotrophic effects of melatonin in male hamsters and its interruption by exposure of the animals to long daily photoperiods. / Reiter, Russel J; Petterborg, Larry J.; Philo, Ronald C.

In: Life Sciences, Vol. 25, No. 18, 29.10.1979, p. 1571-1576.

Research output: Contribution to journalArticle

@article{64fe9634903d4516865e439ab720253a,
title = "Refractoriness to the antigonadotrophic effects of melatonin in male hamsters and its interruption by exposure of the animals to long daily photoperiods",
abstract = "Exposure of adult male Syrian hamsters to artificially shortened photoperiods in the laboratory was followed by gonadal involution. Return of these animals to long days (light:ddark cycles of 14:10) resulted in regrowth of the reproductive organs, following which the animals were refractory to the normally antigonadotrophic effects of daily melatonin injections given late in the afternoon. When hamsters were kept under naturally shortening photoperiods beginning on October 19, their reproductive organs involuted and remained infantile until the following spring when they again recrudesced to adult size. These animals too were refractory to the inhibitory effects of daily afternoon melatonin injections. The refractory period to melatonin was interrupted by exposure of the animals to long days for 22 weeks.",
author = "Reiter, {Russel J} and Petterborg, {Larry J.} and Philo, {Ronald C.}",
year = "1979",
month = "10",
day = "29",
doi = "10.1016/0024-3205(79)90439-9",
language = "English (US)",
volume = "25",
pages = "1571--1576",
journal = "Life Sciences",
issn = "0024-3205",
publisher = "Elsevier Inc.",
number = "18",

}

TY - JOUR

T1 - Refractoriness to the antigonadotrophic effects of melatonin in male hamsters and its interruption by exposure of the animals to long daily photoperiods

AU - Reiter, Russel J

AU - Petterborg, Larry J.

AU - Philo, Ronald C.

PY - 1979/10/29

Y1 - 1979/10/29

N2 - Exposure of adult male Syrian hamsters to artificially shortened photoperiods in the laboratory was followed by gonadal involution. Return of these animals to long days (light:ddark cycles of 14:10) resulted in regrowth of the reproductive organs, following which the animals were refractory to the normally antigonadotrophic effects of daily melatonin injections given late in the afternoon. When hamsters were kept under naturally shortening photoperiods beginning on October 19, their reproductive organs involuted and remained infantile until the following spring when they again recrudesced to adult size. These animals too were refractory to the inhibitory effects of daily afternoon melatonin injections. The refractory period to melatonin was interrupted by exposure of the animals to long days for 22 weeks.

AB - Exposure of adult male Syrian hamsters to artificially shortened photoperiods in the laboratory was followed by gonadal involution. Return of these animals to long days (light:ddark cycles of 14:10) resulted in regrowth of the reproductive organs, following which the animals were refractory to the normally antigonadotrophic effects of daily melatonin injections given late in the afternoon. When hamsters were kept under naturally shortening photoperiods beginning on October 19, their reproductive organs involuted and remained infantile until the following spring when they again recrudesced to adult size. These animals too were refractory to the inhibitory effects of daily afternoon melatonin injections. The refractory period to melatonin was interrupted by exposure of the animals to long days for 22 weeks.

UR - http://www.scopus.com/inward/record.url?scp=0018579322&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018579322&partnerID=8YFLogxK

U2 - 10.1016/0024-3205(79)90439-9

DO - 10.1016/0024-3205(79)90439-9

M3 - Article

VL - 25

SP - 1571

EP - 1576

JO - Life Sciences

JF - Life Sciences

SN - 0024-3205

IS - 18

ER -