Reducing cardiovascular events and end-organ damage in patients with hypertension: New considerations

Laura Harmon, Robert J. Chilton, Craig Spellman

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Hypertension treatment should focus on achieving blood pressure (BP) of < 140/90 mm Hg in most patients and < 130/80 mm Hg in patients with diabetes. Lifestyle modifications play a central role in therapy and should be the first line of treatment in all patients. However, long-term lifestyle changes are rarely achieved and pharmacotherapy is required. The selection of an optimal regimen for each patient will depend on comorbid conditions. Most patients will require combination therapy with ≥ 2 antihypertensive agents to control their BP. The most useful combinations employ drugs from different classes with complementary mechanisms of action, producing additive or synergistic BP reduction with minimal adverse events.

Original languageEnglish (US)
Pages (from-to)7-17
Number of pages11
JournalPostgraduate medicine
Volume123
Issue number2
DOIs
StatePublished - Mar 1 2011

Keywords

  • Antihypertensives
  • Blood pressure control
  • Cardiovascular risk
  • Hypertension

ASJC Scopus subject areas

  • Medicine(all)

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