Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

Medicine and Dentistry

• Mechanistic Target of Rapamycin 100%
• Nuclear Factor 50%
• Lifespan 50%
• Gene 50%
• Cells 50%
• Fibroblast 25%
• Homeostasis 25%
• Mitochondrion 25%
• Mitochondrial Membrane Potential 25%
• Longevity 25%
• Prothrombin 25%
• Oxidative Phosphorylation 25%
• Autophagy 25%
• Mitochondrial Gene 25%
• Mitochondrial Dynamics 25%
• Mitochondrial Transcription Factor A 25%
• Nuclear Respiratory Factor 1 25%
• Reactive Oxygen Species 25%
• Ensure 25%
• Coordination 25%

Biochemistry, Genetics and Molecular Biology

• Intracellular Signaling 75%
• Lifespan 50%
• Mitochondrial Gene 50%
• Normal Human 25%
• Fibroblast 25%
• Nested Gene 25%
• Homeostasis 25%
• Mitochondrion 25%
• Mitochondrial Membrane Potential 25%
• Longevity 25%
• Autophagy 25%
• Oxidative Phosphorylation 25%
• Mitochondrial Dynamics 25%
• Mitochondrial Transcription Factor A 25%
• Nuclear Respiratory Factor 1 25%
• Reduction (Chemistry) 25%
• NFE2L2 25%
• Coordination 25%
• Nuclear Gene 25%

Neuroscience

• Mammalian Target of Rapamycin 100%
• Nuclear Factor 50%
• Reactive Oxygen Species 25%
• Mitochondrion 25%
• Mitochondrial Membrane Potential 25%
• Mitochondrial Dynamics 25%
• Autophagy 25%
• Fibroblast 25%
• Oxidative Phosphorylation 25%
• Mitochondrial Function 25%
• Mitochondrial Gene 25%
• Prothrombin 25%
• NFE2L2 25%
• Mitochondrial Transcription Factor A 25%
• Nuclear Respiratory Factor 1 25%
• Gene 25%
• Coordination 25%