Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics

Chang Weh-Ho, Lin Shih-Ku, Juang Dong-Juiing, Chen Li-Chen, Yang Chih-Hsien, Hu Wei-Herng, Chien Ching-Piao, Yw Francis Lam, Michael W. Jann

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.

Original languageEnglish (US)
Pages (from-to)IN1-IN2,105-112
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Volume17
Issue number1
DOIs
StatePublished - Jan 1993

Keywords

  • RH/HL ratios
  • haloperidol
  • plasma concentrations
  • reduced haloperidol

ASJC Scopus subject areas

  • Pharmacology
  • Biological Psychiatry

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    Weh-Ho, C., Shih-Ku, L., Dong-Juiing, J., Li-Chen, C., Chih-Hsien, Y., Wei-Herng, H., Ching-Piao, C., Lam, Y. F., & Jann, M. W. (1993). Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics. Progress in Neuropsychopharmacology and Biological Psychiatry, 17(1), IN1-IN2,105-112. https://doi.org/10.1016/0278-5846(93)90035-Q