Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement

Pranavi Sreeramoju, Nabilla S. Porbandarwalla, Jorge Arango, Kerry Latham, Daniel L Dent, Ronald M Stewart, Jan E Patterson

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Background: The aim of this study was to examine clinical factors associated with the recurrence of community-onset skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus. Methods: An observational case-comparison study based on a retrospective review of medical records was conducted in a public health system. All patients with community-onset skin and soft tissue infections caused by methicillin-resistant S aureus who underwent operative debridement from January 1999 to December 2003 were included. The outcome of interest was recurrence within 1 year. Results: Two hundred fifty-three patients met the criteria for inclusion. Fifty-three (21%) patients returned with recurrent episodes. These patients were compared with 200 patients (79%) who did not develop recurrence. On multivariate analysis, factors independently predictive of recurrence were medical history of abscess requiring surgical debridement within the previous year (adjusted odds ratio, 2.6; 95% confidence interval, 1.45.0; P = .002) and obesity (adjusted odds ratio, 3.4; 95% confidence interval, 1.48.8; P = .008). Conclusions: Patients with obesity or histories of methicillin-resistant S aureus infection are at significantly increased risk for recurrent soft tissue infection.

Original languageEnglish (US)
Pages (from-to)216-220
Number of pages5
JournalAmerican Journal of Surgery
Volume201
Issue number2
DOIs
StatePublished - Feb 2011

Fingerprint

Soft Tissue Infections
Debridement
Methicillin-Resistant Staphylococcus aureus
Skin
Recurrence
Methicillin Resistance
Obesity
Odds Ratio
Confidence Intervals
Abscess
Medical Records
Case-Control Studies
Multivariate Analysis
Public Health
Infection

Keywords

  • Abscess
  • Epidemiology
  • Methicillin-resistant Staphylococcus aureus
  • Recurrence
  • Risk factors
  • Staphylococcal infections
  • Staphylococcal skin infections
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Surgery

Cite this

Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement. / Sreeramoju, Pranavi; Porbandarwalla, Nabilla S.; Arango, Jorge; Latham, Kerry; Dent, Daniel L; Stewart, Ronald M; Patterson, Jan E.

In: American Journal of Surgery, Vol. 201, No. 2, 02.2011, p. 216-220.

Research output: Contribution to journalArticle

Sreeramoju, Pranavi ; Porbandarwalla, Nabilla S. ; Arango, Jorge ; Latham, Kerry ; Dent, Daniel L ; Stewart, Ronald M ; Patterson, Jan E. / Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement. In: American Journal of Surgery. 2011 ; Vol. 201, No. 2. pp. 216-220.
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