Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms

Yanli Ding, Jean Francis, Jeffrey Kalish, Anita Deshpande, Karen Quillen

Research output: Contribution to journalArticle

Abstract

Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.

Original languageEnglish (US)
Pages (from-to)408-410
Number of pages3
JournalClinical Kidney Journal
Volume9
Issue number3
DOIs
StatePublished - 2016
Externally publishedYes

Keywords

  • Arteriovenous fistula
  • FSGS
  • Kidney transplantation
  • Plasmapheresis
  • Vascular access

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

Fingerprint Dive into the research topics of 'Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms'. Together they form a unique fingerprint.

Cite this