Recombinant murine gamma interferon inhibits Chlamydia trachomatis serovar L1 in vivo

Zhong Guangming Zhong, E. M. Peterson, C. W. Czarniecki, L. M. De la Maza

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Chlamydia trachomatis serovar L1 injected intravenously in mice resulted in systemic nonlethal infections of the animals. Treatment of mice with recombinant murine gamma interferon resulted in a decrease in the number of infectious C. trachomatis organisms recovered from the lungs, spleens, and livers as well as in a decrease of the inflammatory reaction in those organs when assessed 3 and 5 days after challenge.

Original languageEnglish (US)
Pages (from-to)283-286
Number of pages4
JournalInfection and Immunity
Volume56
Issue number1
StatePublished - Jan 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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  • Cite this

    Guangming Zhong, Z., Peterson, E. M., Czarniecki, C. W., & De la Maza, L. M. (1988). Recombinant murine gamma interferon inhibits Chlamydia trachomatis serovar L1 in vivo. Infection and Immunity, 56(1), 283-286.