Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser

C. J. White, S. R. Ramee, T. J. Collins, J. E. Mesa, D. B. Paulsen, Joseph P Murgo

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Laser recanalization of totally occluded swine iliac arteries was performed to assess the safety and efficacy of a lensed fiber laser angioplasty system with a holmium:YAG (2.1 μm) laser. Silica lenses of 1.0 mm, 1.3 mm, and 1.5 mm in diameter attached to the distal end of a 300-μm diameter silica fiber delivered fluences of 79.5 J/cm2, 31.4 J/cm2, and 25.5 J/cm2, respectively. The pusle duration of the laser was 250 μsec and the repetition rate was 4 Hz. The mean length of the total occlusions was 5.3 ± 2.0 cm (range 0.5 cm to 8.0 cm). Successful recanalization was obtained in 16/16 lesions without angiographic vessel perforation. Angiographically significant residual stenoses (~50%) remained in every case following successful laser recanalization. Histologically there was minimal evidence of thermal or acoustic tissue injury; however, in 4 of 16 arteries there was evidence of deep arterial dissection following laser recanalization. We conclude that this lensed fiber coupled with a holmium:YAG laser is a safe and effective method for crossing total occlusions in the relatively straight iliac arteries of this animal model.

Original languageEnglish (US)
Pages (from-to)250-256
Number of pages7
JournalLasers in Surgery and Medicine
Volume11
Issue number3
DOIs
StatePublished - 1991
Externally publishedYes

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Solid-State Lasers
Lasers
Iliac Artery
Silicon Dioxide
Holmium
Laser Angioplasty
Acoustics
Lenses
Dissection
Pathologic Constriction
Swine
Animal Models
Arteries
Hot Temperature
Safety
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery

Cite this

White, C. J., Ramee, S. R., Collins, T. J., Mesa, J. E., Paulsen, D. B., & Murgo, J. P. (1991). Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser. Lasers in Surgery and Medicine, 11(3), 250-256. https://doi.org/10.1002/lsm.1900110308

Recanalization of arterial occlusions with a lensed fiber and a holmium : YAG laser. / White, C. J.; Ramee, S. R.; Collins, T. J.; Mesa, J. E.; Paulsen, D. B.; Murgo, Joseph P.

In: Lasers in Surgery and Medicine, Vol. 11, No. 3, 1991, p. 250-256.

Research output: Contribution to journalArticle

White, CJ, Ramee, SR, Collins, TJ, Mesa, JE, Paulsen, DB & Murgo, JP 1991, 'Recanalization of arterial occlusions with a lensed fiber and a holmium: YAG laser', Lasers in Surgery and Medicine, vol. 11, no. 3, pp. 250-256. https://doi.org/10.1002/lsm.1900110308
White, C. J. ; Ramee, S. R. ; Collins, T. J. ; Mesa, J. E. ; Paulsen, D. B. ; Murgo, Joseph P. / Recanalization of arterial occlusions with a lensed fiber and a holmium : YAG laser. In: Lasers in Surgery and Medicine. 1991 ; Vol. 11, No. 3. pp. 250-256.
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