Recanalization of arterial occlusions with a lensed fiber and a holmium:YAG laser

Christopher J. White, Stephen R. Ramee, Tyrone J. Collins, Juan E. Mesa, Daniel B. Paulsen, Joseph P. Murgo

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Laser recanalization of totally occluded swine iliac arteries was performed to assess the safety and efficacy of a lensed fiber laser angioplasty system with a holmium:YAG (2.1 μm) laser. Silica lenses of 1.0 mm, 1.3 mm, and 1.5 mm in diameter attached to the distal end of a 300‐μm diameter silica fiber delivered fluences of 79.5 J/cm2, 31.4 J/cm2, and 25.5 J/cm2, respectively. The pulse duration of the laser was 250 μsec and the repetition rate was 4 Hz. The mean length of the total occlusions was 5.3 ± 2.0 cm (range 0.5 cm to 8.0 cm). Successful recanalization was obtained in 16/16 lesions without angiographic vessel perforation. Angiographically significant residual stenoses (>50%)remained in every case following successful laser recanalization. Histologically there was minimal evidence of thermal or acoustic tissue injury; however, in 4 of 16 arteries there was evidence of deep arterial dissection following laser recanalization. We conclude that this lensed fiber coupled with a holmium:YAG laser is a safe and effective method for crossing total occlusions in the relatively straight iliac arteries of this animal model.

Original languageEnglish (US)
Pages (from-to)250-256
Number of pages7
JournalLasers in Surgery and Medicine
Volume11
Issue number3
DOIs
StatePublished - 1991
Externally publishedYes

Keywords

  • atherosclerotic swine model
  • laser angioplasty
  • silica lenses

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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