Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae

D. C. Krause, D. K. Leith, J. B. Baseman

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins.

Original languageEnglish (US)
Pages (from-to)830-836
Number of pages7
JournalInfection and immunity
Volume39
Issue number2
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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