Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae

D. C. Krause; D. K. Leith; J. B. Baseman

doi:10.1128/iai.39.2.830-836.1983

Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae

D. C. Krause, D. K. Leith, J. B. Baseman

Microbiology, Immunology & Molecular Genetics

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins.

Original language	English (US)
Pages (from-to)	830-836
Number of pages	7
Journal	Infection and immunity
Volume	39
Issue number	2
DOIs	https://doi.org/10.1128/iai.39.2.830-836.1983
State	Published - 1983

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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title = "Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae",

abstract = "Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins.",

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AB - Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins.

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