Rational use of antibiotics in the critically ill patient

J. M. Koeller

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Despite the advent of newer broad-spectrum antibiotics, infection in critically ill patients still is associated with significant morbidity and mortality. For these patients, who frequently receive inappropriate and excessive empiric antibiotic therapy, it is important to develop rational drug usage criteria. Current economic forces, including personnel shortages and the effects of diagnosis-related groups, are also a critical factor in this patient population. Criteria for rational antibiotic selection are based on patterns of infection and knowledge of the pharmacokinetic and pharmacodynamic properties of individual antibiotics. The development and use of treatment protocols, or algorithms will provide quality patient care for the lowest overall cost.

Original languageEnglish (US)
JournalDICP, Annals of Pharmacotherapy
Volume24
Issue number11 SUPPL.
StatePublished - 1990
Externally publishedYes

Fingerprint

Critical Illness
Anti-Bacterial Agents
Quality of Health Care
Diagnosis-Related Groups
Clinical Protocols
Infection
Patient Care
Pharmacokinetics
Economics
Morbidity
Costs and Cost Analysis
Mortality
Pharmaceutical Preparations
Population
Therapeutics

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Rational use of antibiotics in the critically ill patient. / Koeller, J. M.

In: DICP, Annals of Pharmacotherapy, Vol. 24, No. 11 SUPPL., 1990.

Research output: Contribution to journalArticle

@article{6319a98019c24137a5e9e33420d6f774,
title = "Rational use of antibiotics in the critically ill patient",
abstract = "Despite the advent of newer broad-spectrum antibiotics, infection in critically ill patients still is associated with significant morbidity and mortality. For these patients, who frequently receive inappropriate and excessive empiric antibiotic therapy, it is important to develop rational drug usage criteria. Current economic forces, including personnel shortages and the effects of diagnosis-related groups, are also a critical factor in this patient population. Criteria for rational antibiotic selection are based on patterns of infection and knowledge of the pharmacokinetic and pharmacodynamic properties of individual antibiotics. The development and use of treatment protocols, or algorithms will provide quality patient care for the lowest overall cost.",
author = "Koeller, {J. M.}",
year = "1990",
language = "English (US)",
volume = "24",
journal = "Annals of Pharmacotherapy",
issn = "1060-0280",
publisher = "Harvey Whitney Books Company",
number = "11 SUPPL.",

}

TY - JOUR

T1 - Rational use of antibiotics in the critically ill patient

AU - Koeller, J. M.

PY - 1990

Y1 - 1990

N2 - Despite the advent of newer broad-spectrum antibiotics, infection in critically ill patients still is associated with significant morbidity and mortality. For these patients, who frequently receive inappropriate and excessive empiric antibiotic therapy, it is important to develop rational drug usage criteria. Current economic forces, including personnel shortages and the effects of diagnosis-related groups, are also a critical factor in this patient population. Criteria for rational antibiotic selection are based on patterns of infection and knowledge of the pharmacokinetic and pharmacodynamic properties of individual antibiotics. The development and use of treatment protocols, or algorithms will provide quality patient care for the lowest overall cost.

AB - Despite the advent of newer broad-spectrum antibiotics, infection in critically ill patients still is associated with significant morbidity and mortality. For these patients, who frequently receive inappropriate and excessive empiric antibiotic therapy, it is important to develop rational drug usage criteria. Current economic forces, including personnel shortages and the effects of diagnosis-related groups, are also a critical factor in this patient population. Criteria for rational antibiotic selection are based on patterns of infection and knowledge of the pharmacokinetic and pharmacodynamic properties of individual antibiotics. The development and use of treatment protocols, or algorithms will provide quality patient care for the lowest overall cost.

UR - http://www.scopus.com/inward/record.url?scp=0025222360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025222360&partnerID=8YFLogxK

M3 - Article

C2 - 2270693

AN - SCOPUS:0025222360

VL - 24

JO - Annals of Pharmacotherapy

JF - Annals of Pharmacotherapy

SN - 1060-0280

IS - 11 SUPPL.

ER -