Rapid Proliferation Compensates for Defective Filamentation in Candida albicans Pathogenesis

Research output: Contribution to journalShort surveypeer-review

Abstract

A recent study (Dunker et al.) has shown that a Candida albicans mutant, defective for filamentation, is fully virulent due to rapid cellular proliferation in host tissues. These findings challenge the current paradigm in C. albicans pathogenesis and suggest that defects in one virulence property can be compensated for by enhancements in another.

Original languageEnglish (US)
Pages (from-to)867-868
Number of pages2
JournalTrends in Microbiology
Volume29
Issue number10
DOIs
StatePublished - Oct 2021

Keywords

  • Candida albicans
  • cellular proliferation
  • filaments
  • metabolic adaptation
  • morphology
  • pathogenesis
  • yeast

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases

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