TY - JOUR
T1 - Rapid onset of emphysema associated with diffuse parenchymal disease
AU - Guenter, Clarence A.
AU - Hanley, David A.
AU - Sproule, Brian J.
AU - Coalson, Jacqueline J.
PY - 1979/8
Y1 - 1979/8
N2 - In experimental models pulmonary emphysema may be produced in hours to days; however, in human subjects emphysema commonly develops over a period of many years. In this report we document a case of severe emphysema which developed in less than six months in association with an unexplained illness characterized by dyspnea, hypoxemia and bilateral lung parenchymal disease. There was no hereditary predisposition. The diffuse alveolar injury syndrome must be considered as a potential cause of alveolar disruption.
AB - In experimental models pulmonary emphysema may be produced in hours to days; however, in human subjects emphysema commonly develops over a period of many years. In this report we document a case of severe emphysema which developed in less than six months in association with an unexplained illness characterized by dyspnea, hypoxemia and bilateral lung parenchymal disease. There was no hereditary predisposition. The diffuse alveolar injury syndrome must be considered as a potential cause of alveolar disruption.
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U2 - 10.1016/0002-9343(79)90410-8
DO - 10.1016/0002-9343(79)90410-8
M3 - Article
C2 - 463938
AN - SCOPUS:0018779191
VL - 67
SP - 335
EP - 338
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 2
ER -