Rapid onset of emphysema associated with diffuse parenchymal disease

Clarence A. Guenter, David A. Hanley, Brian J. Sproule, Jacqueline J. Coalson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


In experimental models pulmonary emphysema may be produced in hours to days; however, in human subjects emphysema commonly develops over a period of many years. In this report we document a case of severe emphysema which developed in less than six months in association with an unexplained illness characterized by dyspnea, hypoxemia and bilateral lung parenchymal disease. There was no hereditary predisposition. The diffuse alveolar injury syndrome must be considered as a potential cause of alveolar disruption.

Original languageEnglish (US)
Pages (from-to)335-338
Number of pages4
JournalThe American Journal of Medicine
Issue number2
StatePublished - Aug 1979

ASJC Scopus subject areas

  • Medicine(all)


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