Rapid gastric emptying of an oral glucose solution in type 2 diabetic patients

W. T. Phillips, J. G. Schwartz, C. A. McMahan

Research output: Contribution to journalArticlepeer-review

139 Scopus citations

Abstract

Gastric emptying of a liquid glucose meal was measured with scintigraphic techniques in nine recently diagnosed Type 2 diabetic patients and nine sex- and age-matched nondiabetic control subjects. Seven of the nine Type 2 diabetic patients were receiving oral hypoglycemic therapy which was discontinued the evening prior to the study. The other two diabetic patients were taking no medication. The average gastric half-emptying time was 33.6 min (s.e.m. = 3.2) for the diabetic patients and 64.6 min (s.e.m. = 4.2) for the nondiabetic controls (p = 0.0005). These measurements indicate rapid gastric emptying in Type 2 diabetic patients which may contribute to worsening of glucose control in these patients.

Original languageEnglish (US)
Pages (from-to)1496-1500
Number of pages5
JournalJournal of Nuclear Medicine
Volume33
Issue number8
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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