Rapid gastric emptying of a solid pancake meal in type II diabetic patients

Joyce G. Schwartz, Gary M. Green, Difu Guan, C. Alex McMahan, William T Phillips

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

OBJECTIVE - To estimate the rate of gastric emptying of a solid pancake carbohydrate meal in recently diagnosed asymptomatic type II diabetic patients compared with nondiabetic control subjects. RESEARCH DESIGN AND METHODS - Gastric emptying studies using radiolabeled meals were performed on eight recently diagnosed asymptomatic diabetic patients and on eight sex-, BMI-, and age-matched nondiabetic control subjects. Although a liquid protein drink was administered along with the pancake meal, the radioactivity was adherent to only the pancake portion of the meal. Plasma glucose and serum insulin levels were measured in fasting and postprandial blood samples collected at 15-min intervals up to 120 min after ingestion of the mixed nutrient meal. RESULTS - The average gastric half-emptying time (time it takes for one-half of the meal to empty) was significantly more rapid for the diabetic patients (45.3 ± 4.8 min) when compared with the nondiabetic control subjects (60.4 ± 5.1 min; P = 0.05). The serum insulin concentrations were not statistically different between the two groups. Plasma glucose values were significantly higher in the diabetic patients compared with the nondiabetic control subjects. CONCLUSIONS - Type II diabetic patients with no clinical evidence of neuronal dysfunction have a significantly more rapid rate of gastric emptying of a solid high-carbohydrate meal when compared with nondiabetic control subjects.

Original languageEnglish (US)
Pages (from-to)468-471
Number of pages4
JournalDiabetes Care
Volume19
Issue number5
StatePublished - May 1996

Fingerprint

Gastric Emptying
Meals
Carbohydrates
Insulin
Glucose
Serum
Radioactivity
Fasting
Research Design
Eating
Food
Proteins

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Schwartz, J. G., Green, G. M., Guan, D., McMahan, C. A., & Phillips, W. T. (1996). Rapid gastric emptying of a solid pancake meal in type II diabetic patients. Diabetes Care, 19(5), 468-471.

Rapid gastric emptying of a solid pancake meal in type II diabetic patients. / Schwartz, Joyce G.; Green, Gary M.; Guan, Difu; McMahan, C. Alex; Phillips, William T.

In: Diabetes Care, Vol. 19, No. 5, 05.1996, p. 468-471.

Research output: Contribution to journalArticle

Schwartz, JG, Green, GM, Guan, D, McMahan, CA & Phillips, WT 1996, 'Rapid gastric emptying of a solid pancake meal in type II diabetic patients', Diabetes Care, vol. 19, no. 5, pp. 468-471.
Schwartz JG, Green GM, Guan D, McMahan CA, Phillips WT. Rapid gastric emptying of a solid pancake meal in type II diabetic patients. Diabetes Care. 1996 May;19(5):468-471.
Schwartz, Joyce G. ; Green, Gary M. ; Guan, Difu ; McMahan, C. Alex ; Phillips, William T. / Rapid gastric emptying of a solid pancake meal in type II diabetic patients. In: Diabetes Care. 1996 ; Vol. 19, No. 5. pp. 468-471.
@article{afda7274df4b4f689243e66d7f464833,
title = "Rapid gastric emptying of a solid pancake meal in type II diabetic patients",
abstract = "OBJECTIVE - To estimate the rate of gastric emptying of a solid pancake carbohydrate meal in recently diagnosed asymptomatic type II diabetic patients compared with nondiabetic control subjects. RESEARCH DESIGN AND METHODS - Gastric emptying studies using radiolabeled meals were performed on eight recently diagnosed asymptomatic diabetic patients and on eight sex-, BMI-, and age-matched nondiabetic control subjects. Although a liquid protein drink was administered along with the pancake meal, the radioactivity was adherent to only the pancake portion of the meal. Plasma glucose and serum insulin levels were measured in fasting and postprandial blood samples collected at 15-min intervals up to 120 min after ingestion of the mixed nutrient meal. RESULTS - The average gastric half-emptying time (time it takes for one-half of the meal to empty) was significantly more rapid for the diabetic patients (45.3 ± 4.8 min) when compared with the nondiabetic control subjects (60.4 ± 5.1 min; P = 0.05). The serum insulin concentrations were not statistically different between the two groups. Plasma glucose values were significantly higher in the diabetic patients compared with the nondiabetic control subjects. CONCLUSIONS - Type II diabetic patients with no clinical evidence of neuronal dysfunction have a significantly more rapid rate of gastric emptying of a solid high-carbohydrate meal when compared with nondiabetic control subjects.",
author = "Schwartz, {Joyce G.} and Green, {Gary M.} and Difu Guan and McMahan, {C. Alex} and Phillips, {William T}",
year = "1996",
month = "5",
language = "English (US)",
volume = "19",
pages = "468--471",
journal = "Diabetes Care",
issn = "1935-5548",
publisher = "American Diabetes Association Inc.",
number = "5",

}

TY - JOUR

T1 - Rapid gastric emptying of a solid pancake meal in type II diabetic patients

AU - Schwartz, Joyce G.

AU - Green, Gary M.

AU - Guan, Difu

AU - McMahan, C. Alex

AU - Phillips, William T

PY - 1996/5

Y1 - 1996/5

N2 - OBJECTIVE - To estimate the rate of gastric emptying of a solid pancake carbohydrate meal in recently diagnosed asymptomatic type II diabetic patients compared with nondiabetic control subjects. RESEARCH DESIGN AND METHODS - Gastric emptying studies using radiolabeled meals were performed on eight recently diagnosed asymptomatic diabetic patients and on eight sex-, BMI-, and age-matched nondiabetic control subjects. Although a liquid protein drink was administered along with the pancake meal, the radioactivity was adherent to only the pancake portion of the meal. Plasma glucose and serum insulin levels were measured in fasting and postprandial blood samples collected at 15-min intervals up to 120 min after ingestion of the mixed nutrient meal. RESULTS - The average gastric half-emptying time (time it takes for one-half of the meal to empty) was significantly more rapid for the diabetic patients (45.3 ± 4.8 min) when compared with the nondiabetic control subjects (60.4 ± 5.1 min; P = 0.05). The serum insulin concentrations were not statistically different between the two groups. Plasma glucose values were significantly higher in the diabetic patients compared with the nondiabetic control subjects. CONCLUSIONS - Type II diabetic patients with no clinical evidence of neuronal dysfunction have a significantly more rapid rate of gastric emptying of a solid high-carbohydrate meal when compared with nondiabetic control subjects.

AB - OBJECTIVE - To estimate the rate of gastric emptying of a solid pancake carbohydrate meal in recently diagnosed asymptomatic type II diabetic patients compared with nondiabetic control subjects. RESEARCH DESIGN AND METHODS - Gastric emptying studies using radiolabeled meals were performed on eight recently diagnosed asymptomatic diabetic patients and on eight sex-, BMI-, and age-matched nondiabetic control subjects. Although a liquid protein drink was administered along with the pancake meal, the radioactivity was adherent to only the pancake portion of the meal. Plasma glucose and serum insulin levels were measured in fasting and postprandial blood samples collected at 15-min intervals up to 120 min after ingestion of the mixed nutrient meal. RESULTS - The average gastric half-emptying time (time it takes for one-half of the meal to empty) was significantly more rapid for the diabetic patients (45.3 ± 4.8 min) when compared with the nondiabetic control subjects (60.4 ± 5.1 min; P = 0.05). The serum insulin concentrations were not statistically different between the two groups. Plasma glucose values were significantly higher in the diabetic patients compared with the nondiabetic control subjects. CONCLUSIONS - Type II diabetic patients with no clinical evidence of neuronal dysfunction have a significantly more rapid rate of gastric emptying of a solid high-carbohydrate meal when compared with nondiabetic control subjects.

UR - http://www.scopus.com/inward/record.url?scp=0029971741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029971741&partnerID=8YFLogxK

M3 - Article

C2 - 8732711

AN - SCOPUS:0029971741

VL - 19

SP - 468

EP - 471

JO - Diabetes Care

JF - Diabetes Care

SN - 1935-5548

IS - 5

ER -