Abstract
An equilibration/direct injection gas Chromatographie method has been developed for measurement of enflurane and halothane in whole blood. The method does not require extraction of anesthetic from blood or the use of pre-column devices for preparation of the sample for application to the gas Chromatograph column. By using an "anaerobic" serum vial unit, 1 ml, standards and samples are prepared, equilibrated at 37°C and 10 μl samples of the gas phase injected into the gas Chromatograph. Technical simplicity and reproducibility permit use of this assay under a variety of online conditions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 155-160 |
| Number of pages | 6 |
| Journal | Journal of Pharmacological Methods |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1978 |
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Keywords
- Enflurane
- Gas chromatography
- Halothane
- measurement
ASJC Scopus subject areas
- Pharmacology
Cite this
Rapid gas chromatographie assay for volatile anesthetics in blood. / Jones, David J.
In: Journal of Pharmacological Methods, Vol. 1, No. 2, 1978, p. 155-160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid gas chromatographie assay for volatile anesthetics in blood
AU - Jones, David J.
PY - 1978
Y1 - 1978
N2 - An equilibration/direct injection gas Chromatographie method has been developed for measurement of enflurane and halothane in whole blood. The method does not require extraction of anesthetic from blood or the use of pre-column devices for preparation of the sample for application to the gas Chromatograph column. By using an "anaerobic" serum vial unit, 1 ml, standards and samples are prepared, equilibrated at 37°C and 10 μl samples of the gas phase injected into the gas Chromatograph. Technical simplicity and reproducibility permit use of this assay under a variety of online conditions.
AB - An equilibration/direct injection gas Chromatographie method has been developed for measurement of enflurane and halothane in whole blood. The method does not require extraction of anesthetic from blood or the use of pre-column devices for preparation of the sample for application to the gas Chromatograph column. By using an "anaerobic" serum vial unit, 1 ml, standards and samples are prepared, equilibrated at 37°C and 10 μl samples of the gas phase injected into the gas Chromatograph. Technical simplicity and reproducibility permit use of this assay under a variety of online conditions.
KW - Enflurane
KW - Gas chromatography
KW - Halothane
KW - measurement
UR - http://www.scopus.com/inward/record.url?scp=0018258550&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018258550&partnerID=8YFLogxK
U2 - 10.1016/0160-5402(78)90020-7
DO - 10.1016/0160-5402(78)90020-7
M3 - Article
AN - SCOPUS:0018258550
VL - 1
SP - 155
EP - 160
JO - Journal of Pharmacological and Toxicological Methods
JF - Journal of Pharmacological and Toxicological Methods
SN - 1056-8719
IS - 2
ER -