Rapamycins: Mechanism of action and cellular resistance

Medicine and Dentistry

• Rapamycin 100%
• Mechanistic Target of Rapamycin 80%
• Immunosuppressive Drug 40%
• Anticarcinogen 40%
• Neoplasm 20%
• Carcinogenesis 20%
• Signal Transduction 20%
• Stimulation 20%
• Antifungal Agent 20%
• Cell Growth 20%
• Everolimus 20%
• Phosphoinositide 3-Kinase 20%
• Phosphotransferase Inhibitor 20%
• Organ Transplantation 20%
• S6 Kinase 20%
• Translation Initiation 20%
• Protein Serine Threonine Kinase 20%
• Initiation Factor 4E 20%
• Nutritional Status 20%
• Cyclophilin 20%
• Lactone 20%
• Survival 20%
• Base 20%
• Mechanism of Action 20%
• Inpatient 20%
• Position 20%
• Selectivity 20%
• Parent 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Mammalian Target of Rapamycin 80%
• Anticarcinogen 40%
• Immunosuppressive Agent 40%
• Neoplasm 20%
• Carcinogenesis 20%
• Lactone 20%
• S6 Kinase 20%
• Initiation Factor 4E 20%
• Phosphatidylinositol 3 Kinase 20%
• Everolimus 20%
• Protein Serine Threonine Kinase 20%
• Phosphotransferase Inhibitor 20%
• Cyclophilin 20%
• Base 20%
• Survival 20%

Biochemistry, Genetics and Molecular Biology

• Kinase 80%
• Mammalian Target of Rapamycin 80%
• Signal Transduction 20%
• Serine 20%
• Threonine 20%
• Eukaryotic Initiation Factor 20%
• Cell Growth 20%
• Translation Initiation 20%
• Phosphatidylinositol 20%
• Survival 20%
• Position 20%