Rapamycin: The cure for all that ails

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Target of rapamycin (TOR) signaling stimulates cell growth by regulating protein synthesis in response to a variety of stimuli in a wide range of species and is inhibited by rapamycin, a naturally occurring antifungal compound produced by bacteria and discovered on Easter Island or in the local vernacular, Rapa Nui (rapamycin's namesake). Recently, rapamycin was shown to extend life span for mice, even when administered late in life, suggesting that inhibiting the mammalian TOR pathway may improve health span for people.

Original languageEnglish (US)
Pages (from-to)17-19
Number of pages3
JournalJournal of molecular cell biology
Volume2
Issue number1
DOIs
StatePublished - Dec 1 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

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