Radiotherapy induced soft tissue sarcoma: An unusual case of a dermatofibrosarcoma protuberans

A. Argiris, C. Dardoufas, K. Aroni

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We report a patient with unusual high grade dermatofibrosarcoma protuberans, confirmed by immunohistochemistry, which developed at radiotherapy field margins 5.7 years after radiotherapy for a squamous cell glottic cancer. The sarcoma relapsed locally after inadequate excision and developed lung metastases, as confirmed by fine needle aspiration. Radiotherapy induced soft tissue sarcomas may differ histologically from their spontaneous counterparts. Even a low radiation dose at the field margins can induce a soft tissue sarcoma.

Original languageEnglish (US)
Pages (from-to)59-61
Number of pages3
JournalClinical Oncology
Volume7
Issue number1
DOIs
StatePublished - 1995
Externally publishedYes

Keywords

  • Dermatofibrosarcoma probuterans
  • Radiotherapy adverse effects
  • Second primary neoplasms
  • Soft tissue sarcoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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