Radiation-induced changes of structural and functional properties of human hemoglobin - I. Spectral characterization of irradiated deoxyhemoglobin

Z. Szweda-Lewandowska, M. Puchała, Pawel Osmulski

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Structural changes of human deoxyhemoglobin (deoxyHb) induced by water and ethanol radicals were investigated in this study using absorption spectroscopy. Spectra of deoxyHb samples irradiated under various conditions (the atmosphere of argon or N2O in the absence or presence of ethanol) indicate their conversion into methemoglobin (metHb), hemichrome- and cholehemichrome-like products. The absorbance at the characteristic maxima of these derivatives and also of the oxidized or reduced samples following irradiation depends on the dose of radiation and the conditions employed.

Original languageEnglish (US)
Pages (from-to)39-46
Number of pages8
JournalRadiation and Environmental Biophysics
Volume28
Issue number1
DOIs
StatePublished - Mar 1989
Externally publishedYes

Fingerprint

hemoglobin
functional properties
ethanol
Hemoglobins
ethyl alcohol
Ethanol
Radiation
Methemoglobin
Argon
atomic absorption spectroscopy
radiation
argon
Atmosphere
Absorption spectroscopy
absorbance
structural change
Dosimetry
spectroscopy
Spectrum Analysis
absorption spectroscopy

ASJC Scopus subject areas

  • Radiation
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Environmental Chemistry
  • Environmental Science (miscellaneous)
  • Environmental Science(all)
  • Biophysics
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Radiation-induced changes of structural and functional properties of human hemoglobin - I. Spectral characterization of irradiated deoxyhemoglobin. / Szweda-Lewandowska, Z.; Puchała, M.; Osmulski, Pawel.

In: Radiation and Environmental Biophysics, Vol. 28, No. 1, 03.1989, p. 39-46.

Research output: Contribution to journalArticle

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