Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

J. Brooks Crickard; Corentin J. Moevus; Youngho Kwon; Patrick Sung; Eric C. Greene

doi:10.1016/j.cell.2020.04.056

Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

J. Brooks Crickard
, Corentin J. Moevus
, Youngho Kwon
, Patrick Sung
, Eric C. Greene

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

Rad54 promotes an active mechanism for homology searching during homologous recombination.

Original language	English (US)
Pages (from-to)	1380-1394.e18
Journal	Cell
Volume	181
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2020.04.056
State	Published - Jun 11 2020

Keywords

DNA curtain
DNA double-strand break
Rad51
Rad54
homologous recombination
homology search
motor protein
replication protein A
single molecule

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2020.04.056

Cite this

@article{b317f35963524b7c9670b5b1324dbabd,

title = "Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination",

abstract = "Rad54 promotes an active mechanism for homology searching during homologous recombination.",

keywords = "DNA curtain, DNA double-strand break, Rad51, Rad54, homologous recombination, homology search, motor protein, replication protein A, single molecule",

author = "Crickard, \{J. Brooks\} and Moevus, \{Corentin J.\} and Youngho Kwon and Patrick Sung and Greene, \{Eric C.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = jun,

day = "11",

doi = "10.1016/j.cell.2020.04.056",

language = "English (US)",

volume = "181",

pages = "1380--1394.e18",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "6",

}

TY - JOUR

T1 - Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

AU - Crickard, J. Brooks

AU - Moevus, Corentin J.

AU - Kwon, Youngho

AU - Sung, Patrick

AU - Greene, Eric C.

PY - 2020/6/11

Y1 - 2020/6/11

N2 - Rad54 promotes an active mechanism for homology searching during homologous recombination.

AB - Rad54 promotes an active mechanism for homology searching during homologous recombination.

KW - DNA curtain

KW - DNA double-strand break

KW - Rad51

KW - Rad54

KW - homologous recombination

KW - homology search

KW - motor protein

KW - replication protein A

KW - single molecule

UR - https://www.scopus.com/pages/publications/85085951508

UR - https://www.scopus.com/pages/publications/85085951508#tab=citedBy

U2 - 10.1016/j.cell.2020.04.056

DO - 10.1016/j.cell.2020.04.056

M3 - Article

C2 - 32502392

AN - SCOPUS:85085951508

SN - 0092-8674

VL - 181

SP - 1380-1394.e18

JO - Cell

JF - Cell

IS - 6

ER -

Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

Abstract

Keywords

ASJC Scopus subject areas

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