Quantitative genetics of sexual dimorphism in body fat measurements

Anthony G. Comuzzie, John Blangero, Michael C. Mahaney, Braxton D. Mitchell, Michael P. Stern, Jean W. Maccluer

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

A variance decomposition analysis using maximum likelihood methods was employed to examine the genetic architecture of sexual dimorphism in anthropometric traits in a large pedigreed sample of Mexican American individuals from San Antonio, Texas. For this analysis the magnitude of sexual dimorphism was viewed as arising from a special case of genotype by environment interaction (G × E), that of genotype by sex (G × S). Evidence indicates a marked G × S interaction for 9 of the 12 traits examined and 1 of the 4 indices, findings which are interpreted as indicators of a strong genetic component to the degree of sexual dimorphism expressed in these traits. Such results have important implications for the use and interpretation of these traits in an epidemiological as well as an evolutionary context. © 1993 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)725-734
Number of pages10
JournalAmerican Journal of Human Biology
Volume5
Issue number6
DOIs
StatePublished - 1993
Externally publishedYes

Fingerprint

quantitative genetics
sexual dimorphism
Sex Characteristics
body fat
fat
Adipose Tissue
genotype
Genotype
interaction
Mexican Americans
decomposition analysis
gender
interpretation
Analysis of Variance
evidence
degradation
sampling
methodology

ASJC Scopus subject areas

  • Anatomy
  • Ecology, Evolution, Behavior and Systematics
  • Anthropology
  • Genetics

Cite this

Comuzzie, A. G., Blangero, J., Mahaney, M. C., Mitchell, B. D., Stern, M. P., & Maccluer, J. W. (1993). Quantitative genetics of sexual dimorphism in body fat measurements. American Journal of Human Biology, 5(6), 725-734. https://doi.org/10.1002/ajhb.1310050616

Quantitative genetics of sexual dimorphism in body fat measurements. / Comuzzie, Anthony G.; Blangero, John; Mahaney, Michael C.; Mitchell, Braxton D.; Stern, Michael P.; Maccluer, Jean W.

In: American Journal of Human Biology, Vol. 5, No. 6, 1993, p. 725-734.

Research output: Contribution to journalArticle

Comuzzie, AG, Blangero, J, Mahaney, MC, Mitchell, BD, Stern, MP & Maccluer, JW 1993, 'Quantitative genetics of sexual dimorphism in body fat measurements', American Journal of Human Biology, vol. 5, no. 6, pp. 725-734. https://doi.org/10.1002/ajhb.1310050616
Comuzzie AG, Blangero J, Mahaney MC, Mitchell BD, Stern MP, Maccluer JW. Quantitative genetics of sexual dimorphism in body fat measurements. American Journal of Human Biology. 1993;5(6):725-734. https://doi.org/10.1002/ajhb.1310050616
Comuzzie, Anthony G. ; Blangero, John ; Mahaney, Michael C. ; Mitchell, Braxton D. ; Stern, Michael P. ; Maccluer, Jean W. / Quantitative genetics of sexual dimorphism in body fat measurements. In: American Journal of Human Biology. 1993 ; Vol. 5, No. 6. pp. 725-734.
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