Quantitative cerebral blood flow measurements using MRI

Eric R. Muir, Lora Talley Watts, Yash Vardhan Tiwari, Andrew Bresnen, Qiang Shen, Timothy Q. Duong

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Magnetic resonance imaging can be utilized as a quantitative and noninvasive method to image cerebral blood flow. The two most common techniques used to detect cerebral blood flow are dynamic susceptibility contrast (DSC) perfusion MRI and arterial spin labeling perfusion MRI. Herein we describe the use of these two techniques to measure cerebral blood flow in rodents, including methods, analysis, and important considerations when utilizing these techniques.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press
Pages205-211
Number of pages7
Volume1135
ISBN (Print)9781493903191
DOIs
StatePublished - 2014

Publication series

NameMethods in Molecular Biology
Volume1135
ISSN (Print)10643745

Keywords

  • Arterial spin labeling
  • Cerebral blood flow
  • Dynamic susceptibility contrast
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Muir, E. R., Watts, L. T., Tiwari, Y. V., Bresnen, A., Shen, Q., & Duong, T. Q. (2014). Quantitative cerebral blood flow measurements using MRI. In Methods in Molecular Biology (Vol. 1135, pp. 205-211). (Methods in Molecular Biology; Vol. 1135). Humana Press. https://doi.org/10.1007/978-1-4939-320-7_17