Quantitative cerebral blood flow measurements using MRI

Eric R. Muir, Lora Talley Watts, Yash Vardhan Tiwari, Andrew Bresnen, Qiang Shen, Timothy Q. Duong

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations

Abstract

Magnetic resonance imaging can be utilized as a quantitative and noninvasive method to image cerebral blood flow. The two most common techniques used to detect cerebral blood flow are dynamic susceptibility contrast (DSC) perfusion MRI and arterial spin labeling perfusion MRI. Herein we describe the use of these two techniques to measure cerebral blood flow in rodents, including methods, analysis, and important considerations when utilizing these techniques.

Original languageEnglish (US)
Title of host publicationCerebral Angiogenesis
Subtitle of host publicationMethods and Protocols
PublisherHumana Press
Pages205-211
Number of pages7
ISBN (Print)9781493903191
DOIs
StatePublished - 2014

Publication series

NameMethods in Molecular Biology
Volume1135
ISSN (Print)1064-3745

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Keywords

  • Arterial spin labeling
  • Cerebral blood flow
  • Dynamic susceptibility contrast
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Muir, E. R., Watts, L. T., Tiwari, Y. V., Bresnen, A., Shen, Q., & Duong, T. Q. (2014). Quantitative cerebral blood flow measurements using MRI. In Cerebral Angiogenesis: Methods and Protocols (pp. 205-211). (Methods in Molecular Biology; Vol. 1135). Humana Press. https://doi.org/10.1007/978-1-4939-320-7_17