Quantitative analysis of incipient mineral loss in hard tissues

Anna Matvienko, Andreas Mandelis, Adam Hellen, Raymond Jeon, Stephen Abrams, Bennett Amaechi

Research output: Contribution to journalConference article

8 Scopus citations

Abstract

A coupled diffuse-photon-density-wave and thermal-wave theoretical model was developed to describe the biothermophotonic phenomena in multi-layered hard tissue structures. Photothermal Radiometry was applied as a safe, non-destructive, and highly sensitive tool for the detection of early tooth enamel demineralization to test the theory. Extracted human tooth was treated sequentially with an artificial demineralization gel to simulate controlled mineral loss in the enamel. The experimental setup included a semiconductor laser (659 nm, 120 mW) as the source of the photothermal signal. Modulated laser light generated infrared blackbody radiation from teeth upon absorption and non-radiative energy conversion. The infrared flux emitted by the treated region of the tooth surface and sub-surface was monitored with an infrared detector, both before and after treatment. Frequency scans with a laser beam size of 3 mm were performed in order to guarantee one-dimensionality of the photothermal field. TMR images showed clear differences between sound and demineralized enamel, however this technique is destructive. Dental radiographs did not indicate any changes. The photothermal signal showed clear change even after 1 min of gel treatment. As a result of the fittings, thermal and optical properties of sound and demineralized enamel were obtained, which allowed for quantitative differentiation of healthy and non-healthy regions. In conclusion, the developed model was shown to be a promising tool for non-invasive quantitative analysis of early demineralization of hard tissues.

Original languageEnglish (US)
Article number71660C
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7166
DOIs
StatePublished - Jun 22 2009
EventOptics in Bone Biology and Diagnostics - San Jose, CA, United States
Duration: Jan 24 2009Jan 24 2009

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Keywords

  • Dental
  • Optical properties
  • Photothermal
  • Thermal properties

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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