A double-echo magnetic resonance (MR) phase imaging method was used to measure the time-dependent changes in regional cerebral venous blood oxygenation during neural stimulation. Our results showed that a finger opposition task induced an absolute increase of blood oxygenation level of ΔY = 0.16 ± 0.05 (n = 6), which was measured in the small veins located in the left central sulcus. It was observed that there is a long temporal delay of approximately 27 sec after the onset of the task to reach the steady- state venous oxygenation. This work demonstrated that MRI is a powerful clinical tool for in vivo monitoring of the dynamic nature of organ-specific venous blood oxygenation.
|Original language||English (US)|
|Number of pages||5|
|Journal||Magnetic Resonance in Medicine|
|State||Published - Mar 9 1999|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging