Quantification of dynamic changes in cerebral venous oxygenation with MR phase imaging at 1.9 T

Yijun Liu, Yonglin Pu, Peter T. Fox, Jia Hong Gao

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A double-echo magnetic resonance (MR) phase imaging method was used to measure the time-dependent changes in regional cerebral venous blood oxygenation during neural stimulation. Our results showed that a finger opposition task induced an absolute increase of blood oxygenation level of ΔY = 0.16 ± 0.05 (n = 6), which was measured in the small veins located in the left central sulcus. It was observed that there is a long temporal delay of approximately 27 sec after the onset of the task to reach the steady- state venous oxygenation. This work demonstrated that MRI is a powerful clinical tool for in vivo monitoring of the dynamic nature of organ-specific venous blood oxygenation.

Original languageEnglish (US)
Pages (from-to)407-411
Number of pages5
JournalMagnetic Resonance in Medicine
Volume41
Issue number2
DOIs
StatePublished - Mar 9 1999

Keywords

  • Oxygenation
  • Phase
  • Susceptibility
  • Vein
  • fMRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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