Putative Treponema pallidum cytadhesins share a common functional domain

D. D. Thomas, J. B. Baseman, J. F. Alderete

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Three putative Treponema pallidum ligands (P1, P2, and P3) that bind host fibronectin were characterized by peptide mapping. Papain digestion of each protein yielded a comigrating peptide of approximately 12,000 molecular weight. An antibody to this protein fragment inhibited T. pallidum host cytadherence, indicating that this peptide may be the functional domain of these treponemal adhesins.

Original languageEnglish (US)
Pages (from-to)833-835
Number of pages3
JournalInfection and Immunity
Volume49
Issue number3
StatePublished - 1985

Fingerprint

Treponema pallidum
Peptides
Peptide Mapping
Papain
Fibronectins
Proteolysis
Molecular Weight
Ligands
Antibodies
Proteins

ASJC Scopus subject areas

  • Immunology

Cite this

Thomas, D. D., Baseman, J. B., & Alderete, J. F. (1985). Putative Treponema pallidum cytadhesins share a common functional domain. Infection and Immunity, 49(3), 833-835.

Putative Treponema pallidum cytadhesins share a common functional domain. / Thomas, D. D.; Baseman, J. B.; Alderete, J. F.

In: Infection and Immunity, Vol. 49, No. 3, 1985, p. 833-835.

Research output: Contribution to journalArticle

Thomas, DD, Baseman, JB & Alderete, JF 1985, 'Putative Treponema pallidum cytadhesins share a common functional domain', Infection and Immunity, vol. 49, no. 3, pp. 833-835.
Thomas, D. D. ; Baseman, J. B. ; Alderete, J. F. / Putative Treponema pallidum cytadhesins share a common functional domain. In: Infection and Immunity. 1985 ; Vol. 49, No. 3. pp. 833-835.
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