Pulmonary mucormycosis diagnosed by fine needle aspiration cytology: A case report

Nasir A. Bakshi, Emily E. Volk

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

BACKGROUND: The usefulness of fine needle aspiration cytology (FNAC) in the diagnosis of lung lesions is well documented. Fungal lesions are among nonneoplastic lesions of the lung in which FNAC has proven a useful technique in both munocompromised and immunocompetent patients. These include cryptococcosis, aspergillosis, histoplasmosis and coccidiodomycosis. Pulmonary mucormycosis, an aggressive fungal infection, is rarely diagnosed on FNAC. We report a case of isolated pulmonary mucormycosis diagnosed on FNAC. CASE: A 62-year-old renal transplant recipient with diabetes mellitus and hypertension, asymptomatic for four months, presented with tachypnea, generalized malaise and weakness. Radiologic studies showed an enlarging, cavitating lesion in the right lung. Computed tomography-guided fine needle aspiration performed on the lung lesion showed fungal profiles with broad, ribbonlike, aseptate hyphae with right-angled branching consistent with the Zygomycetes class of fungi, which includes Rhizopus and Mucor species. Fungal cultures confirmed the presence of Rhizopus. The patient underwent right pneumonectomy, was placed on liposomal amphotericin B therapy and discharged with good pulmonary status and stable kidney function. CONCLUSION: FNAC is a useful technique in the diagnosis of pulmonary mucormycosis.

Original languageEnglish (US)
Pages (from-to)411-414
Number of pages4
JournalActa Cytologica
Volume45
Issue number3
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Keywords

  • Aspiration biopsy
  • Lung diseases
  • Mucormycosis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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