Abstract
Histologic findings from segmental lavage material via the fiberoptic bronchoscope were evaluated as a means of diagnosing pulmonary alveolar proteinosis. Active cases of alveolar proteinosis yielded grossly opaque and/or milky effluents. The unique histologic findings in alveolar proteinosis included: (1) very few alveolar macrophages (2) large acellular eosinophilic bodies in a diffuse background of eosinophilic granules, and (3) periodic acid-Schiff staining of the proteinaceous material with a lack of significant alcian blue staining. Thus, the diagnosis of pulmonary alveolar proteinosis can be made by evaluation of the clinical setting and histologic findings of the effluent material from a segmental lavage.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 819-825 |
| Number of pages | 7 |
| Journal | American Review of Respiratory Disease |
| Volume | 121 |
| Issue number | 5 |
| State | Published - 1980 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Pulmonary alveolar proteinosis : The diagnosis by segmental lavage. / Martin, R. J.; Coalson, J. J.; Rogers, R. M.; Horton, F. O.; Manous, L. E.
In: American Review of Respiratory Disease, Vol. 121, No. 5, 1980, p. 819-825.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pulmonary alveolar proteinosis
T2 - The diagnosis by segmental lavage
AU - Martin, R. J.
AU - Coalson, J. J.
AU - Rogers, R. M.
AU - Horton, F. O.
AU - Manous, L. E.
PY - 1980
Y1 - 1980
N2 - Histologic findings from segmental lavage material via the fiberoptic bronchoscope were evaluated as a means of diagnosing pulmonary alveolar proteinosis. Active cases of alveolar proteinosis yielded grossly opaque and/or milky effluents. The unique histologic findings in alveolar proteinosis included: (1) very few alveolar macrophages (2) large acellular eosinophilic bodies in a diffuse background of eosinophilic granules, and (3) periodic acid-Schiff staining of the proteinaceous material with a lack of significant alcian blue staining. Thus, the diagnosis of pulmonary alveolar proteinosis can be made by evaluation of the clinical setting and histologic findings of the effluent material from a segmental lavage.
AB - Histologic findings from segmental lavage material via the fiberoptic bronchoscope were evaluated as a means of diagnosing pulmonary alveolar proteinosis. Active cases of alveolar proteinosis yielded grossly opaque and/or milky effluents. The unique histologic findings in alveolar proteinosis included: (1) very few alveolar macrophages (2) large acellular eosinophilic bodies in a diffuse background of eosinophilic granules, and (3) periodic acid-Schiff staining of the proteinaceous material with a lack of significant alcian blue staining. Thus, the diagnosis of pulmonary alveolar proteinosis can be made by evaluation of the clinical setting and histologic findings of the effluent material from a segmental lavage.
UR - http://www.scopus.com/inward/record.url?scp=0018830853&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018830853&partnerID=8YFLogxK
M3 - Article
C2 - 7406316
AN - SCOPUS:0018830853
VL - 121
SP - 819
EP - 825
JO - American Journal of Respiratory and Critical Care Medicine
JF - American Journal of Respiratory and Critical Care Medicine
SN - 1073-449X
IS - 5
ER -