Abstract
Histologic findings from segmental lavage material via the fiberoptic bronchoscope were evaluated as a means of diagnosing pulmonary alveolar proteinosis. Active cases of alveolar proteinosis yielded grossly opaque and/or milky effluents. The unique histologic findings in alveolar proteinosis included: (1) very few alveolar macrophages (2) large acellular eosinophilic bodies in a diffuse background of eosinophilic granules, and (3) periodic acid-Schiff staining of the proteinaceous material with a lack of significant alcian blue staining. Thus, the diagnosis of pulmonary alveolar proteinosis can be made by evaluation of the clinical setting and histologic findings of the effluent material from a segmental lavage.
Original language | English (US) |
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Pages (from-to) | 819-825 |
Number of pages | 7 |
Journal | American Review of Respiratory Disease |
Volume | 121 |
Issue number | 5 |
State | Published - Jun 27 1980 |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine