Pulmonary alveolar proteinosis: The diagnosis by segmental lavage

R. J. Martin, J. J. Coalson, R. M. Rogers, F. O. Horton, L. E. Manous

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Histologic findings from segmental lavage material via the fiberoptic bronchoscope were evaluated as a means of diagnosing pulmonary alveolar proteinosis. Active cases of alveolar proteinosis yielded grossly opaque and/or milky effluents. The unique histologic findings in alveolar proteinosis included: (1) very few alveolar macrophages (2) large acellular eosinophilic bodies in a diffuse background of eosinophilic granules, and (3) periodic acid-Schiff staining of the proteinaceous material with a lack of significant alcian blue staining. Thus, the diagnosis of pulmonary alveolar proteinosis can be made by evaluation of the clinical setting and histologic findings of the effluent material from a segmental lavage.

Original languageEnglish (US)
Pages (from-to)819-825
Number of pages7
JournalAmerican Review of Respiratory Disease
Volume121
Issue number5
StatePublished - 1980
Externally publishedYes

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Pulmonary Alveolar Proteinosis
Therapeutic Irrigation
Staining and Labeling
Bronchoscopes
Alcian Blue
Periodic Acid
Alveolar Macrophages

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Martin, R. J., Coalson, J. J., Rogers, R. M., Horton, F. O., & Manous, L. E. (1980). Pulmonary alveolar proteinosis: The diagnosis by segmental lavage. American Review of Respiratory Disease, 121(5), 819-825.

Pulmonary alveolar proteinosis : The diagnosis by segmental lavage. / Martin, R. J.; Coalson, J. J.; Rogers, R. M.; Horton, F. O.; Manous, L. E.

In: American Review of Respiratory Disease, Vol. 121, No. 5, 1980, p. 819-825.

Research output: Contribution to journalArticle

Martin, RJ, Coalson, JJ, Rogers, RM, Horton, FO & Manous, LE 1980, 'Pulmonary alveolar proteinosis: The diagnosis by segmental lavage', American Review of Respiratory Disease, vol. 121, no. 5, pp. 819-825.
Martin RJ, Coalson JJ, Rogers RM, Horton FO, Manous LE. Pulmonary alveolar proteinosis: The diagnosis by segmental lavage. American Review of Respiratory Disease. 1980;121(5):819-825.
Martin, R. J. ; Coalson, J. J. ; Rogers, R. M. ; Horton, F. O. ; Manous, L. E. / Pulmonary alveolar proteinosis : The diagnosis by segmental lavage. In: American Review of Respiratory Disease. 1980 ; Vol. 121, No. 5. pp. 819-825.
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