TY - JOUR
T1 - Psychiatric comorbidity is associated with drug use and HIV risk in syringe exchange participants
AU - Disney, Elizabeth
AU - Kidorf, Michael
AU - Kolodner, Ken
AU - King, Van
AU - Peirce, Jessica
AU - Beilenson, Peter
AU - Brooner, Robert K.
PY - 2006/8
Y1 - 2006/8
N2 - The present study evaluated the effects of psychiatric comorbidity on substance use disorder prevalence, HIV risk behavior, and other problem severity in male and female out-of-treatment injection drug users newly registered at a syringe exchange program. Participants (N = 338) were administered the Structured Clinical Interview for the DSM-IV, the Addiction Severity Index, and the Risk Assessment Battery, and classified into one of four diagnostic groups: (1) no antisocial personality disorder (APD) or Axis I psychiatric disorder (N = 162), (2) APD only (N = 74), (3) Axis I psychiatric disorder only (N = 55), or (4) APD plus Axis I psychiatric disorder (N = 47). Psychiatric comorbidity was associated with higher rates of substance use disorder and more HIV risk and other problem severity. In general, participants with both APD and an Axis I disorder exhibited the most problem severity. APD was uniquely associated with higher prevalence for each substance use disorder assessed in this study and with elevated HIV risk. These results support and extend studies conducted with opioid-dependent individuals recruited from treatment and community settings, and reinforce the need to develop interventions to encourage syringe exchange program participants to enroll in treatment.
AB - The present study evaluated the effects of psychiatric comorbidity on substance use disorder prevalence, HIV risk behavior, and other problem severity in male and female out-of-treatment injection drug users newly registered at a syringe exchange program. Participants (N = 338) were administered the Structured Clinical Interview for the DSM-IV, the Addiction Severity Index, and the Risk Assessment Battery, and classified into one of four diagnostic groups: (1) no antisocial personality disorder (APD) or Axis I psychiatric disorder (N = 162), (2) APD only (N = 74), (3) Axis I psychiatric disorder only (N = 55), or (4) APD plus Axis I psychiatric disorder (N = 47). Psychiatric comorbidity was associated with higher rates of substance use disorder and more HIV risk and other problem severity. In general, participants with both APD and an Axis I disorder exhibited the most problem severity. APD was uniquely associated with higher prevalence for each substance use disorder assessed in this study and with elevated HIV risk. These results support and extend studies conducted with opioid-dependent individuals recruited from treatment and community settings, and reinforce the need to develop interventions to encourage syringe exchange program participants to enroll in treatment.
KW - HIV risk behavior
KW - Opioid users
KW - Psychiatric comorbidity
KW - Syringe exchange
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U2 - 10.1097/01.nmd.0000230396.17230.28
DO - 10.1097/01.nmd.0000230396.17230.28
M3 - Article
C2 - 16909065
AN - SCOPUS:33747333920
SN - 0022-3018
VL - 194
SP - 577
EP - 583
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
IS - 8
ER -