Psammoma bodies in neuroendocrine carcinoma of the uterine cervix

V. L. Russin, Philip T Valente, P. Hanjani

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A case of neuroendocrine carcinoma of the uterine cervix with focal papillary clusters and psammoma bodies, features not previously seen in this tumor, is documented. Papanicolaou-stained cervicovaginal smears and pelvic washings are correlated with tissue sections of endocervical curettage, hysterectomy and cul-de-sac biopsy specimens. Although there was some variation in the cytologic features, the tumor cells were generally distinguished by nuclear molding, indistinct nucleoli, finely granular chromatin and scant cytoplasm. Argyrophil-positive intracytoplasmic granules were identified in tissue sections of the tumor. These granules were positive for ACTH and neuron-specific enolase using the immunoperoxidase technique. Ultrastructural studies were consistent with these findings. Neuroendocrine carcinoma of the cervix is therefore a cytologically distinctive tumor in which psammoma bodies may occur.

Original languageEnglish (US)
Pages (from-to)791-795
Number of pages5
JournalActa Cytologica
Volume31
Issue number6
StatePublished - 1987
Externally publishedYes

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Neuroendocrine Carcinoma
Cervix Uteri
Neoplasms
Curettage
Phosphopyruvate Hydratase
Hysterectomy
Immunoenzyme Techniques
Adrenocorticotropic Hormone
Chromatin
Cytoplasm
Biopsy

ASJC Scopus subject areas

  • Cell Biology
  • Anatomy
  • Histology

Cite this

Psammoma bodies in neuroendocrine carcinoma of the uterine cervix. / Russin, V. L.; Valente, Philip T; Hanjani, P.

In: Acta Cytologica, Vol. 31, No. 6, 1987, p. 791-795.

Research output: Contribution to journalArticle

Russin, VL, Valente, PT & Hanjani, P 1987, 'Psammoma bodies in neuroendocrine carcinoma of the uterine cervix', Acta Cytologica, vol. 31, no. 6, pp. 791-795.
Russin, V. L. ; Valente, Philip T ; Hanjani, P. / Psammoma bodies in neuroendocrine carcinoma of the uterine cervix. In: Acta Cytologica. 1987 ; Vol. 31, No. 6. pp. 791-795.
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