Protocols to study dental caries in vitro: Microbial caries models

Bennett T. Amaechi, Livia M.A. Tenuta, Antonio P. Ricomini Filho, Jaime A. Cury

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations


Caries lesions result from the interaction between dental biofilm and sugars. Since the biofilm is an important component in the etiology of the disease, biofilm models have been developed to study the cariogenicity of dietary sugars, as well as the anticaries effect of substances. Two of such models, termed as “static” or “continuous flow,” are described in details here together with their advantages, limitations, and applications.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press
Number of pages12
StatePublished - 2019

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Artificial mouth
  • Continuous flow model
  • Dental caries
  • Dental plaque
  • Microbial model
  • Static model

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology


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