Protein release kinetics of a porous coated implant impregnated with a biodegradable delivery system

C. M. Agrawal; A. Pennick; X. Shen; D. Szygenda; R. C. Schenck

Protein release kinetics of a porous coated implant impregnated with a biodegradable delivery system

C. M. Agrawal, A. Pennick, X. Shen, D. Szygenda, R. C. Schenck

Department of Orthopaedics

Research output: Contribution to conference › Paper › peer-review

1 Scopus citations

Abstract

A system was developed for the continuous and prolonged release of growth factors and other bioactive agents from porous coated prostheses. A fully biodegradable copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) was used for the study. The specimens exhibited a rapid loss in molecular weight and mass. It is possible that due to the low thickness of the polymer layer and intertwining metal fibers, water was able to permeate throughout the material at a fast rate.

Original language	English (US)
Number of pages	1
State	Published - Dec 1 1996
Event	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996

Other

Other	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
City	Toronto, Can
Period	5/29/96 → 6/2/96

ASJC Scopus subject areas

Materials Science(all)

Cite this

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title = "Protein release kinetics of a porous coated implant impregnated with a biodegradable delivery system",

abstract = "A system was developed for the continuous and prolonged release of growth factors and other bioactive agents from porous coated prostheses. A fully biodegradable copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) was used for the study. The specimens exhibited a rapid loss in molecular weight and mass. It is possible that due to the low thickness of the polymer layer and intertwining metal fibers, water was able to permeate throughout the material at a fast rate.",

author = "Agrawal, {C. M.} and A. Pennick and X. Shen and D. Szygenda and Schenck, {R. C.}",

year = "1996",

month = dec,

day = "1",

language = "English (US)",

note = "Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) ; Conference date: 29-05-1996 Through 02-06-1996",

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TY - CONF

T1 - Protein release kinetics of a porous coated implant impregnated with a biodegradable delivery system

AU - Agrawal, C. M.

AU - Pennick, A.

AU - Shen, X.

AU - Szygenda, D.

AU - Schenck, R. C.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - A system was developed for the continuous and prolonged release of growth factors and other bioactive agents from porous coated prostheses. A fully biodegradable copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) was used for the study. The specimens exhibited a rapid loss in molecular weight and mass. It is possible that due to the low thickness of the polymer layer and intertwining metal fibers, water was able to permeate throughout the material at a fast rate.

AB - A system was developed for the continuous and prolonged release of growth factors and other bioactive agents from porous coated prostheses. A fully biodegradable copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) was used for the study. The specimens exhibited a rapid loss in molecular weight and mass. It is possible that due to the low thickness of the polymer layer and intertwining metal fibers, water was able to permeate throughout the material at a fast rate.

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UR - http://www.scopus.com/inward/citedby.url?scp=0030388158&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:0030388158

T2 - Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)

Y2 - 29 May 1996 through 2 June 1996

ER -

Protein release kinetics of a porous coated implant impregnated with a biodegradable delivery system

Abstract

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ASJC Scopus subject areas

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