Prostatic carcinosarcoma 15 years after combined external beam radiation and brachytherapy for prostatic adenocarcinoma: A case report

T. Y. Tseng, D. W. Sevilla, J. W. Moul, Kelly E. Maloney

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

A 65-year-old man with a history of combined pelvic external beam radiation therapy (EBRT) and brachytherapy for prostatic adenocarcinoma 15 years prior underwent total pelvic exenteration for presumed rectal sarcoma with prostatic invasion. Pathology revealed carcinosarcoma of prostatic origin. This patient exhibited the longest reported interval between initial presentation with prostatic adenocarcinoma and development of carcinosarcoma. This case is also the first reported case of prostatic carcinosarcoma occurring after combined EBRT and brachytherapy. The increasing use of such combination high-dose radiation therapy may potentially lead to an increased incidence of secondary malignancies such as prostatic carcinosarcoma in the future.

Original languageEnglish (US)
Pages (from-to)195-197
Number of pages3
JournalProstate Cancer and Prostatic Diseases
Volume9
Issue number2
DOIs
Publication statusPublished - Jun 1 2006

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Keywords

  • Brachytherapy
  • Carcinosarcoma
  • Case reports
  • Prostatic neoplasms
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Urology
  • Cancer Research

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