Prostatectomy tissue for research: Balancing patient care and discovery

Jaime Furman, William M. Murphy, Lori Rice, Peter A. Drew, Perinchery Narayan

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The application of modern technology in basic research often requires fresh tissue from human organs. The acquisition of this tissue challenges the anatomic pathologist to balance the needs of the basic scientist with the requirements of quality patient care. Our experience indicates that fresh tissue adequate for research can be obtained from neoplastic prostate glands without compromising patient care. The process requires dedicated, knowledgeable individuals and extensive documentation. Potential problems include low yield for research studies, loss of all residual carcinoma, compromise of the specimen margin, and unforeseen costs. Best collaborations occur in situations in which basic scientists and anatomic pathologists establish a working relationship and develop a mutually supportive means of funding.

Original languageEnglish (US)
Pages (from-to)4-9
Number of pages6
JournalAmerican journal of clinical pathology
Volume110
Issue number1
DOIs
StatePublished - Jul 1998
Externally publishedYes

Keywords

  • Genetic screening for cancer
  • Prostate cancer
  • RNA screening
  • Translational research

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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