Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde; Elena K. Korngold; Bryan R. Foster; Antonio C. Westphalen; David R. Pettersson; Megan L. Troxell; Jeffry P. Simko; Fergus V. Coakley

doi:10.1016/j.clinimag.2015.12.015

Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde
, Elena K. Korngold
, Bryan R. Foster
, Antonio C. Westphalen
, David R. Pettersson
, Megan L. Troxell
, Jeffry P. Simko
, Fergus V. Coakley

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

Original language	English (US)
Pages (from-to)	365-369
Number of pages	5
Journal	Clinical Imaging
Volume	40
Issue number	3
DOIs	https://doi.org/10.1016/j.clinimag.2015.12.015
State	Published - May 1 2016
Externally published	Yes

Keywords

MR imaging
Pathology
Prostate cancer
Pseudocapsule

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1016/j.clinimag.2015.12.015

Cite this

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title = "Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?",

abstract = "Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.",

keywords = "MR imaging, Pathology, Prostate cancer, Pseudocapsule",

author = "Bonde, \{Apurva A.\} and Korngold, \{Elena K.\} and Foster, \{Bryan R.\} and Westphalen, \{Antonio C.\} and Pettersson, \{David R.\} and Troxell, \{Megan L.\} and Simko, \{Jeffry P.\} and Coakley, \{Fergus V.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc..",

year = "2016",

month = may,

day = "1",

doi = "10.1016/j.clinimag.2015.12.015",

language = "English (US)",

volume = "40",

pages = "365--369",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

number = "3",

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TY - JOUR

T1 - Prostate cancer with a pseudocapsule at MR imaging

T2 - A marker of high grade and stage disease?

AU - Bonde, Apurva A.

AU - Korngold, Elena K.

AU - Foster, Bryan R.

AU - Westphalen, Antonio C.

AU - Pettersson, David R.

AU - Troxell, Megan L.

AU - Simko, Jeffry P.

AU - Coakley, Fergus V.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

AB - Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

KW - MR imaging

KW - Pathology

KW - Prostate cancer

KW - Pseudocapsule

UR - https://www.scopus.com/pages/publications/84959365028

UR - https://www.scopus.com/pages/publications/84959365028#tab=citedBy

U2 - 10.1016/j.clinimag.2015.12.015

DO - 10.1016/j.clinimag.2015.12.015

M3 - Article

C2 - 27133669

AN - SCOPUS:84959365028

SN - 0899-7071

VL - 40

SP - 365

EP - 369

JO - Clinical Imaging

JF - Clinical Imaging

IS - 3

ER -

Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Abstract

Keywords

ASJC Scopus subject areas

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