Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease?

Apurva A. Bonde, Elena K. Korngold, Bryan R. Foster, Antonio C. Westphalen, David R. Pettersson, Megan L. Troxell, Jeffry P. Simko, Fergus V. Coakley

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.

Original languageEnglish (US)
Pages (from-to)365-369
Number of pages5
JournalClinical Imaging
Volume40
Issue number3
DOIs
StatePublished - May 1 2016
Externally publishedYes

Keywords

  • MR imaging
  • Pathology
  • Prostate cancer
  • Pseudocapsule

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Bonde, A. A., Korngold, E. K., Foster, B. R., Westphalen, A. C., Pettersson, D. R., Troxell, M. L., Simko, J. P., & Coakley, F. V. (2016). Prostate cancer with a pseudocapsule at MR imaging: A marker of high grade and stage disease? Clinical Imaging, 40(3), 365-369. https://doi.org/10.1016/j.clinimag.2015.12.015